More realistic models of the bacterial outer membrane

DOI

Current model systems employed in structural studies of bacterial outer membranes rarely mimic the lipid composition accurately. This work is aimed at producing outer membrane models based upon lipopollysaccharides, the predominant lipid component, and including a model outer membrane protein from E. coli. We aim with this proposal to firstly characterise this system as 'half a membrane' at the air liquid interface where using Langmuir methods we have precise control over the surface pressure and hence average area per molecule. The successful completion of this stage will equip us to build more complex models upon solid substrates.

Identifier
DOI https://doi.org/10.5286/ISIS.E.24079757
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/24079757
Provenance
Creator Dr Stephen Holt; Dr Luke Clifton; Professor Jeremy Lakey; Dr Gaetano Mangiapia
Publisher ISIS Neutron and Muon Source
Publication Year 2015
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Photon- and Neutron Geosciences
Temporal Coverage Begin 2010-04-30T13:48:33Z
Temporal Coverage End 2012-09-06T10:33:06Z