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A neutron reflectometry study of the interaction of octanohydroxamate with iron
The interaction of alkyl hydroxamate with iron is of interest in mineral flotation science, corrosion control and also as a model for microbial siderophore chemistry. Long chain... -
CLIC1 Protein Interactions with Model Cell Monlayer Membranes
This dataset has no description
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Function and Structure of Reconstituted Neurotransmitters in biomembranes
Neurotransmitter transporters recognize biogenic amines dopamine, serotonin, noradrenalin and γ-amino butyric acid (GABA). They all belong to the family of... -
Continuation of Proposal (RB820197): The elasto-plastic response of dual-phas...
In the current proposal we propose to test Zr-2.5Nb samples cut at a range of angles (0, 22.5, 45, 67.5 and 90°) in the RD-TD plane in in-situ compression at room temperature.... -
In-situ tension and compression tests in plane strain
This proposal forms part of our larger study into the mechanics of nickel based alloys. In particular we are attempting to correlate the intergranular stress development in... -
Structural study on the 3D arrangement of (hexa-acyl) lipid A in lipid membrane
This study will focus on the structural investigations of the bilayers formed on silicon substrates in which the outer leaf consists of DOPE/LPS mixtures. We aim is to achieve... -
The solution structure of the OmpF¿Colicin N complex in neutral detergent by ...
Gram negative bacteria cause a wide range of diseases. Colicins are protein toxins capable of penetrating the outer membrane barrier and killing the bacteria. Thus they... -
The solution structure of the OmpF¿Colicin N complex in neutral detergent by ...
Gram negative bacteria cause a wide range of diseases including meningitis, bubonic plague, gonorrhoea, diarrhoea, Legionnaires' disease and cholera. Their outer membrane... -
High temperature fatigue loading of Zr-2
Zircaloy-2 and its almost identical sister alloy Zr-4 are used extensively as fuel cladding, as well as other components in nuclear power reactors where it operates at 250-350C... -
Floating Bilayer Mimics of the Gram Negative Bacterial Outer Membrane
The gram-negative bacterial membrane is of extreme medical importance. The two main lipid components of the outer membrane are lipopolysaccharides (LPS's) and DOPE. We will... -
Floating Bilayers Deposited on Au / Fe Surfaces
There is currly great interest in the use of neutron reflection to study model bilayers. We have produced a model membrane system that is strongly associated with the substrate,... -
Application of direct inversion to magnetic contrast datasets.
We have developed an experimental approach using a buried magnetic layer to provide contrast in systems consisting of complex biomolecular layers tethered to gold surfaces. This... -
Using small angle neutron diffraction to describe the status of water in solu...
Fish oocytes and embryos are complex cryobiological objects for which, successful cryopreservation has still not been achieved. This circumstance seriously restricts the... -
In situ loading of Zr-2.5Nb-O at cryogenic temperatures
The proposed experiment will study the deformation of a two phase Zr-2.5Nb alloy at cryogenic temperatures. It forms part of our ongoing long-term project to understand the... -
Chloride Intracellular Channel insertion into Tethered Bilayer Membranes
Part One of the proposal is concerned with the fundamental structure of the TBM and aims to determine: (i) the impact of spacer molecule length on the dimensions of the bilayer... -
Structural characterisation of vaccine-adjuvant interactions using neutron re...
This dataset has no description
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Single Domain pH-Driven DNA Nanoswitch
DNA is an extremely versatile building material for the development and assembly of functional nanostructures and nanodevices. There are numerous examples of DNA based... -
Floating Lipid Bilayers Created by Vesicle Fusion
'Floating LSupported Bilayers' (FSB's) have become the 'standard' systems used for studying membrane systems using reflectivity at ISIS and other facilities. They are reliable,... -
Organisation of Outer membrane protein F at the air/liquid interface
Crystallisation of membrane proteins as a precursor to high resolution structural studies is a significant research bottleneck. We are investigating alternative methods to... -
The solution structure of the OmpF¿Colicin N complex in lipid nanodiscs
We have previously solved the structure by SANS of the complex between the outer membrane protein F of E coi and the toxin colicin N which is a large antibiotic protein. This...
