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Dynamics of amyloid protein fibril elongation using isotope-labelled SANS
This proposal combines optical spectroscopy with neutron scattering using novel labelling strategies to investigate ?amyloid? protein fibrils. Variations in packing and in the... -
SANS experiments on phase separation in duplex stainless steel
Duplex stainless steels have an attractive combination of high strength and corrosion resistance, making them the natural choice in applications such as e.g. pressurised... -
Conformational behaviour of amphiphilic polymethacrylate-poly(acrylic acid) c...
We intend to use small angle neutron scattering to investigate the conformational behaviour of a range of amphiphilic copolymers comprising a hydrophobic methacrylate segment... -
Asymmetric diffusion of water into bicontinuous cubic lipid nanomaterials usi...
In this proposal we will investigate hypothesized asymmetric diffusion of water into lipid cubic (QII) phases. This asymmetric diffusion, which is relevant to the behavior of... -
Zwitterionic Polymers for Lipid Nanodisc Stabilisation
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using... -
Constructing analogues of Gemini and oligomeric surfactants using polyamines
Gemini or oligomeric surfactants, where two or more alkyl chains and headgroups are connected via spacer groups, have interesting and potentially important properties which make... -
Electrochemically Growing Hydrogels to Control Stiffness
At high pH many low molecular weight gelators (LMWG) are dispersed in solution. When a trigger is applied to lower the pH the gelator molecules self-assemble into one...
