28 datasets found

Gene expression is regulated during both the synthesis and the decay of mRNAs. Various pathways of cytoplasmic mRNA decay exist. These include ARE-mediated decay, miRNA-Mediated...

Gemini or oligomeric surfactants, where two or more alkyl chains and headgroups are connected via spacer groups, have interesting and potentially important properties which make...

Many bacteria are able to respire using solid minerals and metals as electron acceptors in the absence of oxygen or other diffusible substrates. In Shewanella oneidensis this...

Lithium ion batteries are the power source of choice for portable electrical devices owing to performance in terms of high specific capacity and reliability. Liquid electrolyte...

Liquid crystalline particles consisting of glycerol dioleate (GDO) / soy phosphatidylcholine (SPC) mixture and stabilised by polysorbate 80 (P80) have proven to be suitable as...

Colloidal dispersions of organic semiconducting nanoparticles (NPs) have shown promise for the generation of active layers in organic solar cells.Composite NPs containing a...

Understanding the nature of protein translocating events through bacterial pores offers an uniqueopportunity to develop novel drug delivery systems, whilst also providing...

Lysosomes are subcellular organelles with acidic interiors (pH 3.5-5), containing enzymes that break down macromolecules and intracellular waste. Controlled release of lysosomal...

Nanoemulsions (NE) i.e. nanoparticles containing a fluid lipid or oil dispersed in water and stabilized by a surfactant particles have attracted considerable attention as...

Polyurethane foams (PUF) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agents...

Endocytosis plays a central role in allowing the selective transport of molecules, via membrane-derived vesicles, into cells. Vesicle formation is controlled by a complex...

Molten chocolate is a semi-solid suspension of (mostly) sugar, but also cocoa and milk solids in oil. In order to allow the sugar grains to flow past each other, either when the...

Diblock co-polymers consist of two polymer chains with different chemical properties tied together at a central linking block. The interactions between the two blocks result in...

The project aims to probe the relationship between surfactant structure, the micelles formed in solution, and the type of drug molecules that the micelles solubilise. Once...

The efficiency of silicon solar cells is limited to 29%. One possible way of breaking this limit uses a process called singlet fission, converting a high energy photon into two...

Protecting biomolecules, such as proteins and enzymes, from the effects of cooling and freezing is important for the storage and handling of pharmaceuticals. Deep eutectic...

This proposal combines optical spectroscopy with neutron scattering using novel labelling strategies to investigate ?amyloid? protein fibrils. Variations in packing and in the...

A shift towards antibody-based cancer treatments has occurred due to their ability to provide targeted cancer treatment with fewer negative side effects than traditional...

The separation of particular lipids in cell membranes into liquid ordered and liquid disorder regions is thought to have a major influence of the functioning of membrane...

Coacervates have been studied for a long time for their unusual properties: they are dense networks of charged polymers that are soluble in water. Instead of flocculating when...