The spectrum of the Be star HD 161306 is shown to vary periodically with a period of ~100-days. The radial velocity of the HeI 6678{AA} emission peak varying in antiphase to the radial velocity of the H{alpha} emission wings component suggests that the star is a binary similar to {phi} Per, 59 Cyg, or FY CMa, i.e. a radiatively interacting Be binary - a rare case among Be stars. This type of object is also called a {phi} Per-type binary or Be + sdO binaries. The range of radial-velocity variations of the strong emission peak in the helium line observed in HD 161306 is about 180km/s, similar to what is observed for these systems. We therefore conclude that HD 161306 may represent another case of a Be star with a hot subdwarf companion.