33 datasets found

This 24min-long, cum-audio, presentation addresses the remarkable alternation involving frontable and unfrontable contrastive foci first examined in Bianchi (2013). The talk...

This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an...

The aim of this experiment is to characterise several novel ionic liquid ¿ oil and ionic liquid ¿ water microemulsions via SANS prior to their use in the synthesis of metallic...

The aim of the present study is to the determine, using specular neutron reflection (SNR), the structure of layers formed by novel tri-chain cationic lipids in combination with...

Time-resolved SANS will be performed to investigate the effect of shear on the fibrillisation of insulin following denaturation. The rheological response will be measured...

This proposal is to perform SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an ongoing...

Nanoemulsions have considerable potential for dermatological drug delivery. Small angle neutron scattering in combination with contrast variation will be used to characterize...

In a previous SAXS experiment at Max-Lab (Sweden) we observed that the thermotropic mesophase transitional behaviour of the monoolein(MO):cholesterol:water system was...

The main objective of the present work is to gain an understanding of the interaction of the cationic protein, cyt c with anionic lipid membranes. This objective will be...

Oxidation of membrane lipids by Reactive Oxygen Species, ROS, in cells may impact ageing, cell apoptosis and cancer. We propose to use our skills obtained studying the oxidation...

We have developed an experimental approach using a buried magnetic layer to provide contrast in systems consisting of complex biomolecular layers tethered to gold surfaces. This...

Proteasome plays an important role in the processing of antigenenic proteins for presentation by the MHC class I pathway. PA28 is an activator of the 20S proteasome, a large...

Here we propose to look at the structure of two phosphocholine lipids, and their larger scale structures in aqueous solution. Depending on the length of the fatty acid chain in...

Mixtures of colloidal particles of essentially two different sizes are commonly used in technological applications such as film formation on surfaces, paper coatings, etc....

Gene delivery vehicles, known as LPD complexes, prepared from mixing cationic lipid vesicles (L) with cationic peptide (P) and DNA (D) have proven to be very effective at...

Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly, leading to interfacial adsorption and solution nano-aggregation....

The present proposal is part of a larger EPSRC project advancing the vibrational spectroscopy of silicate glasses. The project involves the techniques of IR and Raman...

There is considerable effort being put into the modelling of the outer layer of skin, the stratum corneum, because of impending EU restrictions on the use of animal skin for...

Despite interest in microemulsions as drug delivery vehicles, there is a lack of structural understanding to justify the formulations used. The present study examines the use of...

The separation of particular lipids in cell membranes into liquid ordered and liquid disorder regions is thought to have a major influence of the functioning of membrane...