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Further SANS contrast measurements on important protein/DNA interactions from...
This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an... -
Biotemplated hydroxyapatite for radionuclide remediation
Abstract: Apatites (general formula Ca5(PO4)3(OH,F,Cl)) are suitable materials for nuclear waste remediation and storage because they can incorporate actinides in their... -
Charged surfactant adsorption and detergency upon reconstituted plant cuticul...
A number of studies have determined that non-ionic surfactants are capable of altering diffusionrates and transportation of both water and active ingredients thorough the waxy... -
Structural studies of Staufen1 in complex with Upf1, a crucial assembly in ge...
Gene expression is regulated during both the synthesis and the decay of mRNAs. Various pathways of cytoplasmic mRNA decay exist. These include ARE-mediated decay, miRNA-Mediated... -
Kinetics of Muoniated Radicals Studied With Radio Frequency Muon Spin Resonance
Radio-frequency muon spin resonance is a powerful technique for studying free radicals and their reaction kinetics, but it has not yet been used to study complex reactions in... -
Protein nanosheets assembled structures at the air-water interfaces for cell ...
Cell adhesion and proliferation at the surface of liquids such as oil droplets is a surprising phenomenon as it is typically accepted in the field of bioengineering that cells... -
Interaction of amino acid based biosurfactants with model lipid bilayers
N-acyl amino acids are surfactants with attractive applications in different technological fields. They are referred to as mild surfactants because they are commonly considered... -
Rheo-SANS study of peptide gels
Low molecular weight gelators (LMWG) form hydrogels via self-assembly in water under specific conditions to form long, fibrillar structures. Non-covalent forces interactions... -
The solution structure of the OmpF¿Colicin N complex in neutral detergent by ...
Gram negative bacteria cause a wide range of diseases. Colicins are protein toxins capable of penetrating the outer membrane barrier and killing the bacteria. Thus they... -
DNA unwinding mechanism of the archaeal helicase PabMCM in its octameric conf...
The process of cell division requires precise duplication of the genetic material. The separation of the two strands of DNA and the progression of the replisome are driven by... -
Structure-function studies of Replication Protein A and its complexes with DNA.
Replication protein A (RPA), the eukaryotic ssDNA binding protein, is a heterotrimeric protein required for almost all aspects of cellular DNA metabolism. RPA binds... -
SANS contrast measurements on important protein/DNA interactions from RCaH
This proposal is to perform SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an ongoing... -
Changes to the structure of natural lung surfactant, and extracted proteins, ...
The presence of a monolayer of surfactant material at the air-water interface of the lung is crucial for respiratory function. It is well known that exposure to the ubiquitous... -
STRUCTURE OF THE COMPLEX BETWEEN CYTOCHROME P450 REDUCTASE AND CYTOCHROME C
Cytochromes P450 play a key role in drug metabolism in man. Electrons are supplied to the cytochromes by NADPH through the flavoprotein NADPH-cytochrome P450 reductase (CPR).... -
Effect of high temperatures on the adsorption of benzotriazole onto copper/co...
Benzotriazole (BTAH) is a very effective corrosion inhibitor for copper and its alloys in both water and in oils. BTAH is introduced as a corrosion inhibitor in oil based... -
Magnetic contrast reflectometry to resolve transmembrane potential effects on...
The division of bacteria is controlled by the binding of proteins to the inner of the two lipid bilayer membranes that separates the inside of the cell from the outside world.... -
How does oxidative damage change peptide membrane insertion?
The insertion of peptides and proteins into cell membranes is crucial for the functioning of cells, and also for the functioning of a variety of antibacterial reagents. Cells... -
Contrast matching of selectively deuterated glycerides for scattering studies...
Lipid nanoparticles (LNPs) can be formed from glycerides and loaded with diverse cargo for healthcare applications. A key advantage of LNPs over liposomes is the significant... -
Reconstituted lipoprotein particles - Implications of structure and dynamics ...
Neutron scattering will allow to advance the understanding of lipoprotein behavior in solution and at the interface of relevant biological interfaces. Here we focus on HDL... -
Interaction between RNA and lipid monolayers
The objective of the suggested study is to reveal the structure formed when short ssRNA molecules (similar to miRNA) interact with lipid monolayers at the air-water interface....