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Polyoxometallate surfactant adsorption at solution surfaces
Polyoxometallates (POM) are well defined transition metal clusters with a range of interesting catalytic, magnetic and optical properties. To make efficient use of these... -
Oxidation of thin film at the air-water interface of cloud droplets using REA...
The Earth's climate is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects droplet size and optical properties, important effects. Common... -
Elucidating molecular mechanism of membrane disruption by designed α-hel...
We have previously shown that peptides such as G(IIKK)4I-NH2 (G4) can kill bacteria and inhibit cancer cell growth whilst remaining benign to mammalian host cells. We have also... -
Proof of principle: Can ecotoxological partition constants for persistant org...
A proof-of-principle experiment to use the convenient scattering length of perfluorinated alkyl surfactants to measure partitioning to lipids at the air-water interface,... -
Structure and conformation of thermo-responsive nanogels at air/water interfa...
Soft polymeric nanoparticles possess many interesting properties. Those based on N-isopropylacrylamide are surface active and respond to changes in temperature. This give rise... -
NR study of binding of short antimicrobial alpha-helix peptides with model li...
In this work we explore how our rationally designed peptide amphiphiles bind onto lipid monolayers using neutron reflection combined with deuterium labelling to the lipids,... -
Characterisation of newly ordered sapphire blocks
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Using neutron reflectivity from monolayer models of bacterial cell membranes ...
Antimicrobial peptides are being investigated as an alternative to antibiotics, as bacteria seem less able to acquire resistance to them. We have been investigating the way in... -
Antimicrobial Mechanisms of Model Biocides via Their Interaction with Lipopol...
The global increase of bacterial resistance to antibiotics has led to increasing interest in research focusing on the development and characterization of new antimicrobial... -
Modelling of surfactant phase behaviour versus concentration below ambient te...
We wish to understand how the concentration of surfactant mixtures in solution affects adsorption at lower temperatures; in particular, we wish to see how the composition of the... -
The hydrophobic interaction A peptides and a lipid monolayer at the o...
This proposal relates to the study on the fundamental level, the hydrophobic interaction A peptides and a lipid monolayer at the oil-water interface. NR will be used to... -
Effect of temperature on the structure of model wax films as studied by neutr...
Cuticular wax films protect plants by mediating water and nutrient transport from the environment. Surfactant is a key ingredient in agrisprays that can promote the uptake of... -
Study of the interaction of thermoresponsive nanogels with model skin
Skin is an important site for drug delivery. However skin, the stratum corneum which is mainly composed of mixture of lipids, cholesterols and fatty provide a barrier for drug... -
Adsorption of liquid crystal nanostructured particles to model hydrophilic an...
Cubosomes and hexosomes are particles with internal liquid crystal structures of the bicontinuous cubic or reverse hexagonal nanostructures respectively. The nanostructure... -
Neutron Reflectivity Study of Protein Adsorption onto Cell Membrane-inspired ...
We grafted 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer brush from the silicon wafer surface through Cu (0) mediated controlled radical polymerization (CuCRP) to mimic... -
Investigation of surface conjugation of proteins in lipid membrane using neut...
Bilayer lipid membranes and their interactions with the integral or peripheral proteins serve as one of the key mechanism in various cellular functions like communication, cell... -
Impact of surfactant interactions on fate of marine aerosols: NO3-initiated o...
Mixed films of palmitic acid (PA) and galactocerebrosides (GCB) a proxy for marine aerosol exhibit attractive interactions due to H-bonding of galactose and carbonyl head... -
Model anionic/non ionic surfactant adsoption at the interface below room temp...
An experiment performed on INTER last year found extreme non ideal mixing between C12E8/SLES3 at the air water interface: this feature became more extreme as the temperature... -
Lipid monolayers at oil/water interfaces at high surface pressure as model bi...
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Insertion of antimicrobial peptides into phospholipid monolayers at air/liqui...
We have designed a series of cationic peptides with different helix repeats that can kill bacteria but remain benign to mammalian host cells. The selectivity to cell types is...