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The Interaction of Puroindoline-b with Model Phospholipid Bilayers
Puroindolines are basic cystiene rich proteins which possess unique Trp rich domains which are fully conserved in the predominant isoform Pin-a and partially in Pin-b. This... -
Detailed Structure of Phospholipid Bilayers from Multiple Contrast Neutron Re...
In recent monolayer measurements, we have developed models for obtaining detailed structural information of phospholipid structures. The models employ a 'quasimolecular'... -
Phospholipid exchange between tethered bilayers and vesicles
Our objective is to create asymmetric solid surface tethered bilayers (tBLMs) with the the outer leaflet predominately populated by charged phospholipids. tBLMs are produced by... -
Chloride Intracellular Channel insertion into Tethered Bilayer Membranes
Part One of the proposal is concerned with the fundamental structure of the TBM and aims to determine: (i) the impact of spacer molecule length on the dimensions of the bilayer... -
Outer membrane mimics using novel thiol-PC
We have recently shown that dense monolayers of PC can be assembled on gold surfaces using a new omega thiol PC from Avanti. This has two advantages over our previous methods.... -
The Formation of Ion Channels in Phospholipid Bilayers by Puroindoline-a
Puroindolines are basic, cysteine rich proteins of ~13KDa, which have attracted significant interest due to their role in determining the endosperm texture of Wheat and seed...