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Structure of lipid monolayers following oxidative damage
Lipids form the major component of cell membranes, which separate the contents of the cell from the external environment. The oxidation of lipids within biological membranes is... -
Elucidating the effect of BTHC on DMPC monolayers
Plastic bags are used as containers for storage of donated blood. These bags are often made of PVC plasticized with dialkylphthalates (e.g. DEHP), which migrates into the blood... -
Effect of squalene on membrane structure and Amphotericin B resistance in Can...
The yeast Candida glabrata is becoming an increasing cause of infections. We have developed RNA interference tools that allow us to study the virulence and resistance mechanisms... -
Binding studies of Quantum Dots and Pore-Forming Proteins on multi-component ...
Cell membrane being the first line of defence of a complex cell, it forms an important scientific topic to study its encounter with various external entities. Nanoparticles are... -
Interfacial structures and competitive adsorption of amphiphilic millipede po...
Foam stability, appearance and functionality is governed by the thin liquid films between foam bubbles. These films are stabilised by surface active molecules (surfactants and... -
Ibuprofen containing surfactant monolayers: location and stiochiometry of ibu...
An increasing number of potential drug molecules are extremely water insoluble, limiting their commercialisation as medicines. Solubilisation of drug in surfactant micelles is a... -
Structures of cardiolipin-bound cytochrome c in pathological conditions
Cardiolipin (CL) is a structurally unique dimeric phospholipid localized in the inner mitochondrial membrane, which is known to provide essential structural and functional... -
Autoxidation vs. Ozonolysis of Surfactant Mixtures Containing Poly-unsaturate...
Surface-active molecules with water-loving and water-hating parts have been found to contribute substantially to the man-made urban aerosol load originating from cooking... -
Mixed Amino-Acid Based Surfactant Monolayers
Amino acid based surfactants have been known for many years but so far few detailed studies have been carried out on their properties. We are using amino acids extracted from... -
Tuneable Creation of Reservoir Structures at the Air/Water Interface
Recently we have exploited non-equilibrium effects in the preparation of super-efficient polyelectrolyte/surfactant films at the air/water interface spread from the dissociation... -
Effect of polar solvent on the structure of monolayers of phospholipid
It is the aim of the proposal is to perform neutron reflectivity (NR) studies combined with contrast variation to determine the structure of phospholipid monolayers on a... -
Steroidal drug containing dodecyl sulphate monolayers: effect of counterion
An number of potential drugs, including steroidal drugs are extremely water insoluble, limiting their commercialisation as medicines. Solubilisation of drug in surfactant... -
Study of mixed biopolymers at the oil-water interface
Proteins are important in many applications ranging from the stabilisation of emulsions (oil-water interface) to foams (air-water interface). Understanding the relationship... -
Lipodepsipeptides and Brown Blotch Disease in Mushrooms (ii) the role of tola...
Tolaasin is a lipodepsipeptide (lipo = hydrophobic side chain, depsipeptide is an amino acid ring closed in a particular way) produced by strains of Pseudomonas tolaasii, and it... -
Investigation of surface conjugation of proteins in lipid membrane using neut...
Bilayer lipid membranes and their interactions with the integral or peripheral proteins serve as one of the key mechanism in various cellular functions like communication, cell... -
Interfacial structures and competitive adsorption of amphiphilic polymers wit...
Foam stability, appearance and functionality is governed by the thin liquid films between foam bubbles. These films are stabilised by surface active molecules (surfactants and... -
Warm Polar Cloud Chemistry: Can the Halogen "explosion" effect cloud droplet ...
The oxidative processing of pollutants in Polar clouds affects droplet size and optical properties. Polar clouds contain naturally occurring organic lipids forming organic films... -
Effect of glycolipids with therapeutic potential on phase behaviour of model ...
alpha-galactosylceramide (a-GalCer) can activate an immune response through a protein-mediated cell signalling event. The effect of a-GalCer on local membrane structure is... -
Interactions of lipidic cubic nanoparticles with model lipid biomembranes at ...
Lipidic cubic nanoparticles (LCNPs) have been extensively studied as therapeutic agents and delivery systems due to their biocompatibility, ease of drug encapsulation and... -
Surface structure of monolayers formed by novel di- and tri-chain cationic li...
The aim of the present study is to the determine, using specular neutron reflection (SNR), the structure of layers formed by novel tri-chain cationic lipids in combination with...