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A SESANS study of the structures of bile salts-polymer complexes that facilit...
Nearly 40% new drugs are poorly water-soluble.To achieve good oral absorption of these compounds, solubilisation in the gut fluid is extremely important.Water-soluble polymers... -
Pinning down pinholin: a structural mechanism to explain how peptide adsorpti...
We will use specular and off-specular neutron reflectivity to provide a structural mechanism for the way in which the amphipathic peptide pinholin controls bacterial cell lysis... -
Testing the efficacy of the spin echo technique combined with the dynamical t...
The sensitivity of the Spin Echo Resolved Grazing Incidence Scattering (SERGIS) to scattering geometry and sample specifications has been tested at OFFSPEC on gratings with... -
Using SERGIS to characterise monolayer buckling on the approach to collapse
Thin films just one or a few molecules thick can play an important role in controlling many important phenomena. This includes the lipid monolayers that coat the surface of our... -
Using SERGIS, SESANS and NR to probe nanoscale cavities created within templa...
Nanoporous membranes fabricated by polymerization around soluble templates have found many applications in (bio)sensors, charge storage devices, filtration and catalysis.... -
Tuning the Magnetic Properties of γ-Fe2O3 Fe3O4 Thin Films for Atom Tr...
In this work we will investigate how the magnetic properties of nanometer thick iron-oxide films can be manipulated by heating them in air. Our preliminary results indicate that... -
Determining the nanostructure of PCBM in thin film photovoltaics
Organic photovoltaics (OPVs) are a low cost alternative to existing photovoltaic materials. The efficiency of OPVs is steadily increasing towards the point where their cost per... -
SESANS study of phase segregation in microemulsion polymerisations
Spin echo small-angle neutron scattering (SESANS) beamtime is requested to study the growth of polymer nanolatices in novel microemulsion systems. The natural incompatibility of... -
An In-Situ Study of the Formation of Amyloid Fibrils at Polymer Surfaces Usin...
We propose to study the formation of lateral features during insulin amyloid formation on polymer substrates using off-specular neutron reflectivity. This will be done by... -
Investigating the response of lipid bilayers to physically structured substrates
The functionality of biological membranes is closely tied to their structural behavior. To understand this behavior we propose to study the conformality of artificial lipid... -
Critical Opalescence in Binary Liquid Mixtures
In this proposal, we would like to investigate how a binary organic mixture approaches its critical point over unprecedented length and time scales, from the micron range down... -
Understanding Phospho-L-Serine (PS) role in the Organization of Cholesterol C...
Our goal is to understand the role of POPS, a lipid component only found in the inner leaflet of plasma membrane, in the organization of cholesterol in cell membranes. Our... -
SE-SANS investigation of natural shale swelling under oil-well conditions
Water-based drilling fluids are increasingly being used for oil and gas exploration. Unfortunately, their use leads to clay swelling which occurs in exposed sedimentary rocks... -
Studying Artificial Ripple Structures
In addition to smoothing and self-affine roughening ion bombardment of solid surfaces can result in ripple and dot structures with nanometer scale dimensions. This method... -
Large Fractal Aggregates in Silica Rubber Nanocomposites
The self assembled structure of silica aggregates in polybutadiene rubber is vital to our understanding of dynamic energy dissipation effects in tyres. Previous experiments on... -
Assembly of functionalized nanoparticles at fluid interfaces
To try to understand the variation in surface tension as a function of functionalized gold nanoparticle particle and SDS concentration, we will make measurements of the specular... -
Exploring colloidal assembly in periodic nano-confinements using neutron spin...
Colloids in confinements have structural and dynamic properties in some cases very different from bulk properties. In particular, when the width of the confinement is few times... -
Order in the bulk and at the surface of dispersions of colloidal particles
Highly ordered dispersions of charged polymer particles that are tens or hundreds of nanometres diameter can be prepared. These are useful model systems for self-assembly and... -
Organisation of Latex Particles in Solution and at the Water/Sapphire Interface
Polystyrene latex represents an excellent model system for studies of the physical properties of colloidal particles. The materials can be prepared with controlled size, and... -
Understanding the structure of constrained polymer thin-films: ¿artificial an...
The Mayes' group at UEA is world-leading in investigating core-shell nanoparticles as a promising format for 'synthetic antibodies', based on molecular imprinting. One of the...
