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Water-based gels of half N-acetylated chitosans; potential pharmaceutical exc...
These experiments are part of a much broader programme at the University of Reading. focused on the use of water-soluble half-acetylated chitosan as a mucoadhesive polymer,... -
Radiation induced changes in block copolymer micelles
Block copolymer micelles have been used to encapsulate various chemotherapeutic drugs, which can be delivered to the tumour site using the so-called Enhanced Permeation and... -
Concentration of small acids using complex coacervates
Volatile fatty acids (VFAs) are widely used chemicals, which serve as precursors for e.g., polymers. These VFAs can be produced through unsustainable petrochemical routes.... -
Self-assembly in biosurfactants and biosurfactant / surfactant mixtures
This proposal is part of a new project which is a collaboration between Oxford, Newcastle, Ulster, and Unilever on the development of sustainable laundry detergents, using... -
SANS studies of mixed phospholipid:sterol vesicles and their interaction with...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Using SANS2D to resolve the opening of MscL clusters in proteoliposomes in re...
In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock. Although crucial for protecting cells, as with all ion channels, they have the... -
Polymer adsorption from fluorinated media in polymer stabilised drug suspensions
The formation of stable particle dispersions are essential to the success of a wide range of commercial products from inks, paints and foodstuffs to cosmetic and pharmaceutical... -
Formulating polymer solutions to stabilise polymeric foams
Polyurethane foams (PUF) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agents... -
Interactions of Cationic Surfactants with Phospholipid Vesicles: Influence of...
Surfactants are frequently used in personal care products to improve the wetting and oil solubilizing qualities of the products, which also leads to the skin irritation by... -
Composite Electrospun Fibres based on Food waste
Thus proposal seeks to explore the nature of electrospun composite fibres where the polymeric material contains a substantial quantity of biopolymer obtained from food waste -... -
Encapsulation of hydrophobic species into cat-anionic micelles in polymer sol...
This proposal continues our investigations into film forming polyelectrolyte-surfactant solutions. We have found that mixed cat-anionic micelle systems offer greater control... -
Kinetics of the formation of eumelanin and its intermediates
The proposed research project is targeted to the investigation of the characteristics of eumelanin, a heterogeneous material insoluble in water and in any organic solvent, as... -
Gold-loaded microgels
Recent results show that gold nanoparticles (Au-NPs) can be included into microgels (MGs). UV-visible spectra (Figure 1) suggest the original Au-NP sols retain their size and... -
Dynamics of amyloid protein fibril growth using isotope-labelled SANS
This proposal aims use a novel approach whereby deuterated amyloid peptide fibrils are givenhydrogenated growing ends, and analysed using SANS. The data will enable us to... -
Changes of phospholipid aggregate morphology induced by phospholipase hydrolysis
We propose to look at the interaction of the aggregates two phospholipids form with two phospholipase (PL) enzymes, PLA2 and PLC, which hydrolyse different ester groups in the... -
SANS study of hollow nanoparticles and their solvent release
Hollow nanoparticles (HNP) have been successfully used for encapsulation and controlled release of biochemicals such as drugs, DNA, and dyes. However no in-situ method has been... -
SANS study of engine oil gelation
Metal carbonate particles dispersed in dodecane and stabilised with alkyl salicylate surfactants have been shown to aggregate when trace water is added. We have found that... -
Is there a CMC for surfactants in non-aqueous solvents?
The aim of this project is to use SANS to determine if a critical micelle concentration (CMC) exists for the formation of inverse micelles in non-polar solvents. The CMC is a... -
Structure of alkylated aza-crown ether inverse micelles
Ion transfer through fluid-fluid interfaces plays decisive roles in many natural and industrial processes. In studies of Cu(II) transport by Permeation Liquid Membrane (PLM)... -
Surfactant induced gelation of TEMPO-oxidized cellulose; Using betaine-based ...
Our group has been working cellulose nanofibrils (OCNF) which form hydrogels in the presence of certain additives. Previously, we have studied the effect of salt, single...
