103 datasets found

Neutron reflection has been successfully used to measure the conformation of proteins adsorbed at the oil/water interface. However, in several such experiments, hexadecane has...

In a series of neutron spin-echo experiments (NSE) on the proteins alcohol dehydrogenase (ADH) and phosphoglycerate kinase (PGK) large scale large amplitude domain motions with...

Gram negative bacteria cause a wide range of diseases including meningitis, bubonic plague, gonorrhoea, diarrhoea, Legionnaires' disease and cholera. Their outer membrane...

The objective of the suggested study is to reveal the structure formed when short ssRNA molecules (similar to miRNA) interact with lipid monolayers at the air-water interface....

Neutron scattering will allow to advance the understanding of lipoprotein behavior in solution and at the interface of relevant biological interfaces. Here we focus on HDL...

Lipid nanoparticles (LNPs) can be formed from glycerides and loaded with diverse cargo for healthcare applications. A key advantage of LNPs over liposomes is the significant...

The insertion of peptides and proteins into cell membranes is crucial for the functioning of cells, and also for the functioning of a variety of antibacterial reagents. Cells...

The division of bacteria is controlled by the binding of proteins to the inner of the two lipid bilayer membranes that separates the inside of the cell from the outside world....

Benzotriazole (BTAH) is a very effective corrosion inhibitor for copper and its alloys in both water and in oils. BTAH is introduced as a corrosion inhibitor in oil based...

Cytochromes P450 play a key role in drug metabolism in man. Electrons are supplied to the cytochromes by NADPH through the flavoprotein NADPH-cytochrome P450 reductase (CPR)....

The presence of a monolayer of surfactant material at the air-water interface of the lung is crucial for respiratory function. It is well known that exposure to the ubiquitous...

This proposal is to perform SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an ongoing...

Replication protein A (RPA), the eukaryotic ssDNA binding protein, is a heterotrimeric protein required for almost all aspects of cellular DNA metabolism. RPA binds...

The process of cell division requires precise duplication of the genetic material. The separation of the two strands of DNA and the progression of the replisome are driven by...

Gram negative bacteria cause a wide range of diseases. Colicins are protein toxins capable of penetrating the outer membrane barrier and killing the bacteria. Thus they...

Low molecular weight gelators (LMWG) form hydrogels via self-assembly in water under specific conditions to form long, fibrillar structures. Non-covalent forces interactions...

N-acyl amino acids are surfactants with attractive applications in different technological fields. They are referred to as mild surfactants because they are commonly considered...

Cell adhesion and proliferation at the surface of liquids such as oil droplets is a surprising phenomenon as it is typically accepted in the field of bioengineering that cells...

Radio-frequency muon spin resonance is a powerful technique for studying free radicals and their reaction kinetics, but it has not yet been used to study complex reactions in...

Gene expression is regulated during both the synthesis and the decay of mRNAs. Various pathways of cytoplasmic mRNA decay exist. These include ARE-mediated decay, miRNA-Mediated...