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Conformational analysis of subtilin / lipid II binary antibiotic/target membr...
Antibiotic resistance is pathogenic bacteria is a major clinical problem. Resistance to all antibiotiotic classes, currentl yin clinical use, has been reported. By contrast, the... -
Structure formation in catanionic surfactant/polymer templated inorganic film...
Recently we have been investigating the mineralization of polymer-surfactant films to create thicker and more robust self-supporting membranes. Our previous experiments used the... -
Surface properties of biogenic polyaminesurfactant mixtures
Polyions and biogenic polyamine are ubiquitous in many important biochemical functions. We propose here to use neutron reflectivity to investigate their potential to induce and... -
Effect of temperature on the structure of model wax films as studied by neutr...
Cuticular wax films protect plants by mediating water and nutrient transport from the environment. Surfactant is a key ingredient in agrisprays that can promote the uptake of... -
Organisation of Outer membrane protein F at the air/liquid interface
Crystallisation of membrane proteins as a precursor to high resolution structural studies is a significant research bottleneck. We are investigating alternative methods to... -
On the peculiarities of the structure of particle stabilised foam
Many formulated products pass through or end up as foams, comprising immiscible millimeter sized bubbles dispersed into an aqueous continuous phase. Frequently, surfactants or... -
Probing the structure of polymer stabilised foams
Polyurethane foams (PUFs) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agent... -
The Effect of the Head Group on Multilayering of Alkanoic Alkyl Ester Sulphon...
We have shown that under certain conditions multilayer adsorption of surfactants occurs at the air-water interface. in which case the system becomes a powerful wetting agent (it... -
Surface multilayer structures in hydrophobin-Tween mixtures
Increased environmental pressures and awareness is promoting a major drive towards an increased use of biosurfactants to produce more biosustainable and biodegradable consumer... -
Modelling of surfactant phase behaviour versus concentration below ambient te...
We wish to understand how the concentration of surfactant mixtures in solution affects adsorption at lower temperatures; in particular, we wish to see how the composition of the... -
manipulating surface adsorption usinf ethoxylated polyelectrolytes
The strong interaction between polyelectrolytes and ionic surfactants can result in pronounced surface adsorption and the formation of surface multilayer structures. This... -
Antimicrobial Mechanisms of Model Biocides via Their Interaction with Lipopol...
The global increase of bacterial resistance to antibiotics has led to increasing interest in research focusing on the development and characterization of new antimicrobial... -
Surface adsorption of short peptide surfactants
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation.... -
Neutron reflection study of effects of non-ionic alkyl ethoxylates on model w...
We propose to use NR to study the structural features of the model wheat wax films formulated from the known main components of long chain primary alcohols and an ester. By... -
Interaction of lignosulphonates with model surfactant systems by neutron refl...
With the biobased economy growing substantially and pressure to reduce reliance on palm and crude oil derived materials, it is vital that the Home and Personal Care industry... -
Interaction of Surfactant with Model Lipid Membranes: Influence of Surfactant...
Skin becomes a target of drug delivery because the transdermal routes are non-invasive, can be self-administrated, improve patient compliance and can provide release for long... -
More realistic models of the bacterial outer membrane
Current model systems employed in structural studies of bacterial outer membranes rarely mimic the lipid composition accurately. This work is aimed at producing outer membrane... -
Interactions of de Novo Designed Antimicrobial Lipopeptides with Model Leafle...
In this work, we propose to exploit the unique capability of neutron reflection (NR) to study the structural changes of multi-component lipid monolayer models mimicking... -
Understanding the nature of perfume / surfactant interactions at interfaces
This proposal is part of a funded (CASE) project, aimed at understanding the delivery of benefit actives (perfumes) to interfaces and the development of new self-assembled... -
More than the sum - oxidation behaviour of mixed fatty acid monolayers
Single molecule thin films of various surface-active species are found on the surface of water bodies from the sea down to microscopic spray droplets. These films affect the...
