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The Interaction of Grp1 with Membranes Containing Signalling Phospholipids
This dataset has no description
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Mechanism of fibrous aggregate formation of caseinates as a function of proce...
This dataset has no description
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Magnetic contrast reflectometry to resolve transmembrane potential effects on...
The division of bacteria is controlled by the binding of proteins to the inner of the two lipid bilayer membranes that separates the inside of the cell from the outside world.... -
Examining Hydration Dynamics and the Glass Transition Behaviour of Keratin Fi...
Proteinwater interactions establish and shape the thermodynamic landscape that governs the folding, structure, stability, mechanics and activity of proteins, and thus... -
Interaction of Low Density Lipoproteins (LDL) with Model Mammalian Cell Membr...
Atherosclerosis and subsequent clinical complication is one of the biggest killers in the western world, with a death toll reaching 16.7 million deaths per year. Although many... -
Effect of End Group on RAFT-Polymers for Lipid Nanodisc Stabilisation
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using... -
SANS study of the interaction of model plant leaf waxes with non-ionic surfac...
The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving... -
Entropy change of protein and water during the denaturation of cytochrome P450s
Cytochrome P450s are ubiquitous hemeprotein monooxygenases that catalyse numerous biochemical reactions, and the investigation on them is of significance to both the protein... -
Lipid exchange between high density lipoprotein (HDL) and model phosphatidylc...
Lipoproteins are the main carriers of lipids in the body. HDL is believed to favor cholesterol removal and decrease the risk to develop atherosclerosis and related... -
Neutron reflectometry of an atopic dermatitis stratum corneum skin model
Atopic dermatitis (AD) is a chronic inflammatory skin condition affecting up to 20% of children and 3% of adults, resulting in significant reduction in quality of life and costs... -
Dynamics of Protein-Confined Water in Polymer Vesicles: A Feasibility Study
When we confine water in extremely small spaces it starts to move extremely slowly. This behaviour is critical to helping biological molecules like proteins function normally.... -
The Mechanism of Bam Mediated Outer Membrane Protein Folding
The proteins of the outer membrane of Gram-negative bacteria are critical for bacterial survival,from providing basic physiological functions, to impairing virulence and... -
Amphiphilic Block Polymers based on Polypeptides as Versatile Drug Nanocarriers
Novel self-assembling di-block polymers have been designed multi-component polymer-drug conjugates for the delivery of cytotoxic drugs to solid tumours. It is known that the... -
Bacterial membrane disruption by layered double hydroxide particles
Layered double hydroxides (LDHs) have recently been identified as interesting drug delivery vehicles due to their ability to intercalate guest molecules. Additionally, LDHs... -
Investigating the structure of modular ionogels for catalysis, biocatalysis, ...
Ionogels are a new class of soft matter that have only really become subject of detailed research in the past decade. As a result, much of the contemporary literature is still... -
Magnetic contrast NR to resolve MscL opening under PXG challenge
In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock, but, as with all ion channels, they have the potential to act as an Achilles heel,... -
Dynamics of yeast lipid membranes
A cell membrane can contain hundreds of different lipid molecules, but our understanding of the dynamics of cell membranes is very limited. As a result of a collaboration... -
Structure of Confined Albumin Layers
In the context of a project in collaboration with ISIS that focuses on structural studies under mechanical confinement, with a specific focus on biological lubricants, the... -
Morphology and Phase Diagram of Thermoresponsive Polymer-Protein Conjugates
Using an enzyme mediated conjugation method we have prepared well-designed protein-polymer conjugates using a model protein, green fluorescent protein (GFP) with... -
Zwitterionic Polymers for Lipid Nanodisc Stabilisation
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using...
