8,763 datasets found

We propose to investigate the interfacial adsorption of a series of water-soluble single chain PC surfactants using neutron reflection, focusing on assessing the effects of...

With the beamtime requested we plan to employ small-angle neutron scattering (SANS) to study novel nanocolloidal drug carriers prepared using lipids, surfactants and...

We wish to investigate the pH-dependence of the strong interfacial interaction of 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) with poly(silicic) acid at the air-water...

Following our previous study of adsorption of globular lysozyme and BSA, we continue to explore how another globular protein hydrophobin adsorbs at the oil/water interface by...

Although surfactant detergency is well understood above 30 C, actions of surfactants below 30 C are not well established. In the era of energy saving and environment caring, we...

We propose to use neutron reflection to study the interfacial adsorption of 2 novel bispecific therapeutic antibodies at the silicon oxide/water interface. To enpower each of...

We have previously studied the adsorption of anti-beta-hCG at the hydrophilic silicon oxide/water interface and the subsequent binding by antigen hCG. We propose to extend this...

Gastric mucus is a vital component for the protection of the stomach from the highly acidic gastric secretions, preventing autodigestion and providing mechanical protection....

This proposal constitutes part of our ongoing study towards understanding the adsorption of collagen based polypeptide and its interaction with ionic surfactants at the...

Short peptide sequences such as KLVFFAE form well defined beta sheet structures. Their further templating through hydrophobic interactions and hydrogen bonding is the principal...

Doxil® is a marketed liposomal formulation containing the anticancer drug doxorubicin. Recently, SAXS measurements have evidenced a crystalline fibrillar structure for the...

Lipopeptide surfactants are highly effective at reducing interfacial tension. However, there is a general lack of understanding of the relationship between their molecular...

This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an...

Dendrimers are nanosized macromolecules with hyperbranched structures that are capable of loading all kinds of active agents for biodelivery. They are monodisperse in terms of...

Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key...

UBEST (Understanding the biogeochemical buffering capacity of estuaries relative to climate change and anthropogenic inputs) project aimed to improve the global understanding of...

Insights into past marine carbon cycling and water mass properties can be obtained through controlled laboratory experiments with accurate seawater carbonate system (C-system)...

Three vent fields (Menez Gwen, Lucky Strike, Snake Pit) of the Mid-Atlantic Ridge have been studied during six cruises between 2012 and 2016 on three different research vessels...

Monthly anomalies of geochemical parameters in the Caribbean Sea calculated from the MULTIOBS_GLO_BIO_BGC_3D_REP_015_010 and MULTIOBS_GLO_BIO_CARBON_SURFACE_REP_015_008...

The gill is the organ by which many toxic metals are taken up by crustaceans. Fe2+ is known to precipitate at its surface, a phenomenon recently observed in some tropical...