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Membrane interactions of a viral scission protein
Influenza virus is a pathogen of great medical importance that causes seasonal epidemics and sporadic pandemics. Among the least understood events of the influenza virus... -
Solid-supported lipid bilayers for studying mechanosensitive ion channels: to...
Bacterial membranes contain safety valves called mechanosensitive ion channels, which protect the bacterium from changes in the osmotic pressure of their environment. However,... -
Probing the effects of oxidative stress on the membrane binding of alpha-synu...
Neutron reflectometry will be used to characterise the cellular membrane binding interaction of alpha-synuclein under conditions mimicking oxidative stress. Alpha-synuclein is... -
Membrane-stacking properties of myelin proteins
Myelin is the multilamellar structure that ensheaths axons and accelerates nervous impulses in the nervous system. The fine structure of myelin remains to be further... -
Assembling Biomimetic layers on monolayers of Gold Nanoparticles
Gold provides a high quality surface on which to arrange biomolecules such as proteins since we can use cysteine amino acids to deliver gold thiol chemical bonds which can... -
Humic acid interactions with alumina surface and the effect of perfluoroalkyl...
In the soil environment, organic matter such as humic acid has a strong influence on the behaviour of organic pollutants such as perfluoroalkyl substances (PFASs) and their... -
Nanodiscs films at the air-water interface
Nanodiscs are self assembled complexes of phospholipids and a class of amphipathic helical proteins termed membrane scaffold proteins . The proteins and lipids self-assemble... -
The structure and orientation of the Bam complex in the Gram-negative outer m...
The proteins of the outer membrane of Gram-negative bacteria are critical for bacterialsurvival, from providing basic physiological functions, to aiding virulence and... -
Understanding Surfactant-Semiconducting Polymer Interactions for Optimisation...
This dataset has no description
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Using neutron reflectivity from monolayer models of bacterial cell membranes ...
Antimicrobial peptides are being investigated as an alternative to antibiotics, as bacteria seem less able to acquire resistance to them. We have been investigating the way in... -
Probing the interactions of chitosan with lipid bilayers to elucidate its ant...
Chitosan is a linear polysaccharide that is biocompatible and biodegradable. Chitosan has a number of unique chemical and biological features including its cationic nature and... -
Adsorption and activity of Thermomyces lanuginosus Lipase (TLL) at the oilwat...
The purpose with the proposed project is to provide a better understanding of structural changes in interfacial lipid layers due action of lipolytic enzymes. In this study we... -
Cationic surfactants adsorbed to titanium dioxide-effect of pH and added elec...
Titanium dioxide (TiO2) is used in a wide range of applications from medical and dental implants to treatment of contaminated air and water streams. However many of the... -
Neutron scattering to characterise protein interactions with solid-liquid int...
Objectives of this proposal aim to shed light on how adsorption processes such as protein A chromatography, used to purify biologics, affect protein propensity for aggregation.... -
The use of lipid sponge-like nanoparticles as carriers for macromolecules and...
Conventional ways to administer and deliver drugs have reached its limitations. These methods can be still used for small and simple molecules. However, new carriers have to be... -
Purothionin binding to model fungal lipid membranes
Purothionins and defensins are basic, amphiphilic, cysteine-rich and low molecular weight plant defence proteins. These proteins are active against a broad range of... -
Do cardiolipins play a role for the mode of action of antimicrobial peptides?...
Antimicrobial peptides (AMPs), also called host defense peptides, are part of the innate immune system of essentially all species, from bacteria themselves to mammals to protect... -
Modification of an adsorbed cationic layer by anionic surfactants below the CMC
In this proposal, we request beamtime to study the unexpected behaviour of a strongly bound bilayer of the cationic surfactant didodecyldimethylammonium bromide on the anionic... -
Binding studies of Quantum Dots and Pore-Forming Proteins on multi-component ...
Cell membrane being the first line of defence of a complex cell, it forms an important scientific topic to study its encounter with various external entities. Nanoparticles are... -
Interfacial structures and competitive adsorption of amphiphilic millipede po...
Foam stability, appearance and functionality is governed by the thin liquid films between foam bubbles. These films are stabilised by surface active molecules (surfactants and...
