-
The role of tryptophan in puroindoline/purothionin cooperative binding to bio...
The puroindoline (PIN) and purothionin (PTH) families of polypeptides both occur in wheat and are implicated in antipathogenic defence mechanisms, and of interest for potential... -
Multilayering of Isostearic Methyl Ester Sulphonate at the Air-Aqueous Interf...
Surfactants usually form a single layer of molecules at the surface of water. We have shown that under certain conditions more than one layer may form. in which case the system... -
Neutron Reflectivity Study of Protein Adsorption onto Cell Membrane-inspired ...
We grafted 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer brush from the silicon wafer surface through Cu (0) mediated controlled radical polymerization (CuCRP) to mimic... -
Lipopolysaccharide Functions as Bacterial Receptors to Antimicrobial Peptides
Neutron reflection (NR) is well established for studying molecular films such as lipid monolayers. Its high depth resolution combined with deuterium labelling can determine the... -
Chain Length and Surface Coverage of Surface Grafted Polypeptoids on Protein ...
Inhibition of non-specific protein adsorption to surfaces is critical for proper functioning of medical devices. Different approaches have been developed for producing surfaces... -
Understanding the interfacial behaviour of bile salts to better engineer lipi...
The current project aims at elucidating how bile salts (BS) structure influences their interfacial behaviour and their impact on fat digestion. Neutron reflectivity (NR) is the... -
Organization of mitochondrial membranes upon oxidative stress: Impact on apop...
Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). The mitochondrial apoptotic pathway is a... -
Surface composition in the physical developer process for latent fingerprint ...
Physical developer (PD) is a latent fingerprint development technique that is highly effective on paper and related surfaces, notably banknotes. The process exploits a redox... -
Floating Bilayers Deposited on Au / Fe Surfaces
There is currly great interest in the use of neutron reflection to study model bilayers. We have produced a model membrane system that is strongly associated with the substrate,... -
Probing the spatial distribution of fluorophores entering nanoscale pores in ...
We wish to make specular NR measurements on fluorophore functionalization of amine-functionalized polypyrrole (PPy-NH2) films. The critical issue is film penetration of solution... -
Proving ground-state ordering in Artificial Spin-Ice systems formed by sub-10...
The main purpose of the experiment proposed here is to study the effects of thermalisation on Artificial Spin-Ice (ASI) systems formed by nanomagnets with sub-100 nm lateral... -
Elucidating the Membrane Interaction Mechanism of Chloride Intracellular Chan...
Chloride Intracellular Channels (CLICs) are a family of 6 proteins that have in common a C-terminal CLIC module and chloride-selective ion channel activity. CLIC1 is a 241... -
Aquatic Methane Adsorption and Desorption on Minerals
In this project we propose to study the adsorption of methane onto a model mineral surface. This type of study is crucial to the understanding of the temperature dependence of... -
Spontaneously Segregated Polymer Brush Structure
This study intends to elucidate how molecular hairy or brush-like structures form on different flat surfaces. When molecule chains form a densely packed assembly on a surface... -
Studying Artificial Ripple Structures
In addition to smoothing and self-affine roughening ion bombardment of solid surfaces can result in ripple and dot structures with nanometer scale dimensions. This method... -
Dynamic Nuclear Polarization in GaAs by electrical spin injection
We propose to measure the dynamic nuclear polarization in a GaAs-based structure caused by electrical injection of a spin-polarized current using polarized neutron... -
The use of lipid sponge-like nanoparticles as carriers for macromolecules and...
Biological membranes do not only occur as planar bilayer structures, but bilayers have also been shown to, depending onthe lipid composition, curve into intriguing 3D... -
Interactions between Designed Antimicrobial Lipopeptides and Inner Membrane L...
Neutron reflection will be used to reveal the structural changes from different inner membrane leaflet models upon interacting with a group of antimicrobial lipopeptides with... -
Interfacial adsorption of monoclonal antibody and antigen binding
Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element... -
Competitive and cooperative adsorption of lysozyme and human serum albumin
All solid surfaces in contact with biological systems form a protein corona and the nature of this corona determines the further response of the biosystem to that solid surface...
