749 datasets found

Ionic liquids (ILs) have attracted considerable interest as a promising “green” substitute for organic solvents. Although, toxicity of some ILs is a cause for concern, recent...

The lung surfactant is a film coating the alveolus of the lung. We want to characterize the structure of this film at the air-water interface at a molecular level. This will...

The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving...

This proposal is a continuation of our previous experiment on NIMROD (Rb 1520094), where we studied aqueous solutions of trehalose (33 wt% trehalose) as well as myoglobin in the...

How proteins fold from their linear sequence into their functional structures is still not understood and the misfolding of proteins is linked to a variety of diseases - such as...

Amphiphilic protein surfactant interactions are becoming increasingly important in all aspects of soft condensed matter for drug delivery, flavour enhancement, foam stability...

The yeast Candida glabrata is becoming an increasing cause of infections. We have developed RNA interference tools that allow us to study the virulence and resistance mechanisms...

Tissue Factor (TF) is the membrane protein responsible for the initiation of the blood coagulation process [1]. In case of a vessel injury, the TF is exposed to the blood stream...

Marine biofouling compromises function and reliability of marine equipment, causing considerable economic and environmental damage. Biocides for fouling prevention are...

Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce...

Biological membrane mimics are a bottle neck in biophysical studies today. The need to develop advanced models that actually represent the properties of specific cellular...

The proteins of the outer membrane of Gram-negative bacteria are critical for bacterial survival, from providing basic physiological functions, to impairing virulence and...

Atherosclerosis and subsequent clinical complication is one of the biggest killers in the western world, with a death toll reaching 16.7 million deaths per year. Although many...

This proposal seeks to shed light on the functional and structural characteristics of a specific membrane protein - cytochrome P450 reductase (abb. POR) - part of the cytochrome...

Biological membrane mimics are a bottle neck in biophysical studies today. The need to develop advanced models that actually represent the properties of specific cellular...

Acyl L-Carnitines are a group of novel surfactants with attractive physical and biological properties associated with their head group charge features. This work proposes to use...

Human dihydroorotate dehydrogenase (DHODH) is an integral membrane protein found in mitochondria involved in the biosynthesis of pyrimidines. DHODH oxidizes dihydroorotate with...

Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug...

The proteins of the outer membrane of Gram-negative bacteria are critical for bacterial survival, from providing basic physiological functions, to impairing virulence and...

Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs...