85 datasets found

Recent research has demonstrated the potential of nanosized delivery systems for routine use in many diseases, eg cancer, viral diseases and rheumatoid arthritis [1,2], due to...

We propose to investigate antimicrobial peptides that self-assemble into well-defined nanostructures. Previous SAXS results have shown that the peptides form rather robust...

While peripheral membrane protein-lipid interactions were originally considered to be solely electrostatic in nature, it is now accepted that they encompass more complicated,...

The detailed functional characterization of an outer membrane for C. glutamicum is a major challenge for the future since it raises several questions regarding the resistance of...

We propose to perform combined measurements of neutron reflectometry (NR) and impedance spectroscopy (IS) to investigate the structure/function relationship of tethered bilayer...

Antibiotic resistance is pathogenic bacteria is a major clinical problem. Resistance to all antibiotiotic classes, currentl yin clinical use, has been reported. By contrast, the...

This proposal seeks to characterise the hydrophobic interaction of thermoresponsive nanogels designed for drug delivery through the skin with a lipid monolayer as a function of...

Atherosclerosis is the leading cause of death in western society, its consequences such as strokes and heart attacks arise from the build-up of plaques of fat which accumulate...

Lung surfactant protein B, SP-B, interacts with lipids at the air-water interface of the lung where its presence is vital for correct respiratory function. SP-B and its...

The crystallisation of membrane proteins is of great interest, not least, to the pharmaceutical industry. We have recently begun a project aiming to investigate the role played...

The proteins of the outer membrane of Gram-negative bacteria are critical for bacterialsurvival, from providing basic physiological functions, to aiding virulence and...

Nanodiscs are self assembled complexes of phospholipids and a class of amphipathic helical proteins termed membrane scaffold proteins . The proteins and lipids self-assemble...

Despite the increasing use of nanoparticles (NPs), our current knowledge of how NPs interact with the human body or the environment remains limited. Of a number of mechanisms, a...

Novel Gemini surfactants (protophanes and cyclophanes) have been synthesised as model biological anion receptors, and their critical micelle concentrations determined by surface...

The aim of the present neutron reflectivity proposal is to obtain stereochemical and kinetic information studying the thermo-lyotropic behaviour of the lipid mixture DOPC-DDAB...

Internally supported liposomes (ISLs) are composed of polymeric spheres enclosed by liposomes. Although very little research has been done on ISLs, understanding their...

This data publication contains a high resolution molecular dataset of a study aiming to trace variations in organic carbon sourcing along the Kali Gandaki River in Central...

This dataset provides the raw SIMS data for the publication "Mechanisms of lipid preservation in archaeological clay ceramics revealed by mass spectrometry imaging" by Simon...

This dataset includes NMR spectra raw data generated in this study, Negative stain EM micrographs for αSyn fibrils in the presence of anle138b and mass spectrometry data for the...

Investigating pottery function requires optimal preservation of both ceramic vessels and organic residues related to vessel use. If these criteria are met then opportunities...