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Using SANS2D to resolve the opening of MscL clusters in proteoliposomes in re...
In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock. Although crucial for protecting cells, as with all ion channels, they have the... -
Architecture of lipid-protein nanoglobules in velvet worm prey capture slime
Fiber fabrication in animals is an important inspiration source for polymeric materials. Velvet worm prey capture slime represents a unique way of fiber fabrication by using... -
SANS Studies of Nanostructures of Microfluidically Fabricated lipid Nanoparti...
We have developed a new approach for forming lipid nanoparticles (LNP) with and without interfering RNA and DNA from a microfluidic setup. The LNPs are formed by an ionisable... -
Magnetic interparticle coupling and magnetisation process in TbCu2 superantif...
Magnetic nanoparticles are being investigated intensively. They show a core/shell structure in which different magnetic orderings are possible.The superantiferromagnetic TbCu2... -
Using SANS to understand the structural basis for the rheology of molten choc...
Molten chocolate is a semi-solid suspension of (mostly) sugar, but also cocoa and milk solids in oil. In order to allow the sugar grains to flow past each other, either when the... -
Magnetic nanostructures of Fe-Ag and Fe-Au granular thin films
Nanogranular thin films of FexM100-x (M=Au,Ag; x=7,20,39) are an excellent system to study the magnetism of nanoparticles in diamagnetic matrices coupled by direct, RKKY and... -
Biomolecular Cryoprotection in Deep Eutectic Solvents
Protecting biomolecules, such as proteins and enzymes, from the effects of cooling and freezing is important for the storage and handling of pharmaceuticals. Deep eutectic... -
Film formation and water uptake in macroRAFT latices studied by contrast vari...
Latex is made from tiny polymer particles in water. Latex films are used in paints and to manufacture adhesives & inks. Latex is good for the environment, as it does not... -
Structure and interactions in model and real anti-reflective coatings
This proposal seeks to exploit contrast variation SANS to study a multi-component system, spanning a wide range of colloidal length scales. The multi-component system under... -
Encapsulation of Non-Steroidal Anti-Inflammatory Drugs Using Novel Pluronic G...
The research topic is encapsulation of a hydrophobic drug, flurbiprofen, using novel amphiphilic graft copolymers (AGCs). The AGCs of interest are shown in Figure 1: Preliminary... -
Polymer-phospholipid nanodiscs: Modification of polymer hydrophilicity.
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied nanodisc formation... -
SANS Contrast Matching Studies of Radiation-grafted Anion-exchange Membranes
We request two days beam time on SANS2D for the study of radiation-grafted anion-exchange membranes, both dry and hydrated under different ratios of D2O/H2O. These materials... -
Film formation and water uptake in macroRAFT latices studied by contrast vari...
Latex is made from tiny polymer particles in water. Latex films are used in paints and to manufacture adhesives & inks. Latex is good for the environment, as it does not... -
Film formation in macroRAFT latices studied by SANS
Latex is made from tiny polymer particles in water. Latex films are used in paints and to manufacture adhesives & inks. Latex is good for the environment, as it does not... -
Self-assembled thermoresponsive fluoropolymer nanostructures for MRI tumour i...
Nanoparticles made of polymers containing fluorine have promising applications since magnetic resonance imaging using fluorinated contrast agents (19F MRI) enables enhanced... -
SANS characterization of carbonate reservoir formation and evolution
Geologists are increasingly realizing the unique perspective that neutron scattering offers for unlocking the complex geologic histories of rocks. In this study, we propose to... -
Aggregation of random co-polymers
This proposal builds upon the successful study of a cationic copolymer capable of forming polymer micellar-like aggregates, simply by reducing pH (D33 at ILL 9-12-433 see... -
Conformations in partially mixed block copolymers of partially deuterated pol...
Nascent 'disentangled' block copolymers of Ultra-high Molecular Weight Polyethylene (UHMWPE) with a reduced number of entanglements were synthesized having protonated (hPE) and... -
Tuning the Molecular Exchange Kinetics of Self-Assembled Antimicrobial Peptid...
Self-assembling antimicrobial peptides (SAAMPs) are promising candidates for antibiotic substitutes. The self-assembled structure provides proteolytic stability to the... -
pH responsive Core-Shell-Corona (CSC) micellar complexes: Corona- and teleche...
Coacervation is an electrostatically-driven liquid-liquid phase separation process, resulting from the association of oppositely charged macro-ions. In this framework,...