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Effect of Phosphatidylserine lipids on Tissue Factor structure and function i...
Tissue Factor (TF) is the membrane protein responsible for the initiation of the blood coagulation process [1]. In case of a vessel injury, the TF is exposed to the blood stream... -
Hydration and chain entanglement in random poly(HEMA-co-PEG10MA) brushes
Marine biofouling compromises function and reliability of marine equipment, causing considerable economic and environmental damage. Biocides for fouling prevention are... -
Magnetic Profile of a Novel Magnetic Quantum Well
Proximity effects associated with magnetic impurities embedded in paramagnetic Pd have been known to produced so-called giant moments. It has been demonstrated that confining Fe... -
Biosurfactant conventional surfactant mixing. Where nature does it better ?
Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce... -
Biological membrane mimics made of deuterated lipids extracted from E. coli
Biological membrane mimics are a bottle neck in biophysical studies today. The need to develop advanced models that actually represent the properties of specific cellular... -
Temperature dependence of magnetic dead-layers: a possible route to novel 2D ...
We propose to investigate the temperature dependence of magnetic dead-layer thickness in amorphous ferromagnetic CoFeTaB films on Si and GaAs semiconductor substrates. Magnetic... -
Surfactant Adsorption in Multi Metal Deposition Fingerprint Enhancement
Multi metal deposition (MMD) is a new latent fingerprint enhancement technique that is extremely effective on plastics, including drug wraps and explosives wrapping; it is also... -
Seizing Membrane Proteins - Cytochrome P450 Reductase in Nanodiscs
This proposal seeks to shed light on the functional and structural characteristics of a specific membrane protein - cytochrome P450 reductase (abb. POR) - part of the cytochrome... -
Co-surfactancy of oil-soluble and water-soluble surfactants at the oil-water ...
A technique we have recently developed enables us to simply produce stable, homogenous and thin oil layers, using polymer surfactants, in a simple manner on water. These are... -
Spatially profiling internal microstructure changes during redox driven rapid...
The redox driven swelling and deswelling of conducting polymers has been termed Electronic Muscle actuation. One application of this property is as a sphincter-like valve in a... -
Membrane reconstitution of human dihydroorotate dehydrogenase using lipid-det...
Human dihydroorotate dehydrogenase (DHODH) is an integral membrane protein found in mitochondria involved in the biosynthesis of pyrimidines. DHODH oxidizes dihydroorotate with... -
The role of disulphide bridges in the adsorption of globular proteins at the ...
Following our previous study of adsorption of globular lysozyme and BSA at the oil/water interface by neutron reflection, we continue to explore how unfolding of globular... -
Antibiotic binding to a bacterial outer membrane model containing oriented pr...
The Outer Membranes (OM) is a feature of many pathogenic bacteria. It is important as a barrier to antibiotics & the site of human-bacteria interaction. However bacteria are... -
Polymerisation of Styrene in PEI-Surfactant Films on Si Wafers
We have been studying the formation of solid polymer-surfactant films formed from cationic surfactants with PEI. We wish to use the highly organised mesostructures formed in the... -
pH-Responsive Polyelectrolyte Brushes Studied by Neutron Reflectivity and in ...
pH-responsive polymer brushes comprise of long polymer chains of either a weak acid or base chemically attached to a surface. Depending upon the degree of ionisation along the... -
Magnetic moment of EuO in spin filtering magnetic tunnel structures
EuO is the ferromagnetic oxide semiconductor with the highest demonstrated value of conduction band exchange splitting (0.6 eV), which makes it at present one of the most... -
Understanding the insertion of antibiotic toxins into the gram negative outer...
The gram-negative bacterial membrane is of extreme medical importance. Two of its major components are lipopolysaccharides (LPS's) and integral membrane proteins. Porins are... -
Using the nano discs approach at surfaces to determine the relation between s...
Membrane bound proteins continue to be to date the most elusive molecules in nature, since they are only functional in the lipid bilayer. We have developed a method to study... -
Protein exchange at the solid/liquid interface
The balance of proteins adsorbed at a surface is important in a wide range of situations, e.g. implants, nanoparticles. The accepted model is that rapidly diffusing proteins... -
Polyoxometallate surfactant adsorption at solution surfaces
Polyoxometallates (POM) are well defined transition metal clusters with a range of interesting catalytic, magnetic and optical properties. To make efficient use of these...
