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Biological membrane mimics made of deuterated lipids extracted from E. coli
Biological membrane mimics are a bottle neck in biophysical studies today. The need to develop advanced models that actually represent the properties of specific cellular... -
Carrier recombination lifetime spectroscopy with photo-MuSR: Measuring bulk a...
Having established the carrier lifetime spectroscopy in intrinsic Si with the photo-MuSR method in our previous beam times, we recently found its sensitivity for both bulk and... -
Surfactant Adsorption in Multi Metal Deposition Fingerprint Enhancement
Multi metal deposition (MMD) is a new latent fingerprint enhancement technique that is extremely effective on plastics, including drug wraps and explosives wrapping; it is also... -
Seizing Membrane Proteins - Cytochrome P450 Reductase in Nanodiscs
This proposal seeks to shed light on the functional and structural characteristics of a specific membrane protein - cytochrome P450 reductase (abb. POR) - part of the cytochrome... -
Cation ordering in silicate spinel Ni2SiO4
Silicate spinels are important minerals in the transition zone region of the Earth and in order to understand seismic signals from these depths (550-660 km) we need to know the... -
Membrane reconstitution of human dihydroorotate dehydrogenase using lipid-det...
Human dihydroorotate dehydrogenase (DHODH) is an integral membrane protein found in mitochondria involved in the biosynthesis of pyrimidines. DHODH oxidizes dihydroorotate with... -
Testing protein location in curved lipid bilayers using oriented lipid cubic ...
This proposal will test whether membrane proteins within lipid cubic phases preferentially sit in more or less curved bilayer regions, using our recent advances in preparing... -
Interfacial Adsorbtion from Nematic Mixtures
The aim is to determine the amount of absorbtion of the one component of a mixture at the nemtic/air interface using neutron reflection. The host material in the mixture will be... -
The role of disulphide bridges in the adsorption of globular proteins at the ...
Following our previous study of adsorption of globular lysozyme and BSA at the oil/water interface by neutron reflection, we continue to explore how unfolding of globular... -
Antibiotic binding to a bacterial outer membrane model containing oriented pr...
The Outer Membranes (OM) is a feature of many pathogenic bacteria. It is important as a barrier to antibiotics & the site of human-bacteria interaction. However bacteria are... -
Polymerisation of Styrene in PEI-Surfactant Films on Si Wafers
We have been studying the formation of solid polymer-surfactant films formed from cationic surfactants with PEI. We wish to use the highly organised mesostructures formed in the... -
The interaction of novel gold supraparticles with model lipid membranes
Engineered nanoparticles (NPs) found large application in medicine as theranostic materials for the diagnosis and therapy of many diseases. The understanding of the interactions... -
In-situ internal strain measurements in textured austenitic steel under strai...
Internal strains and dislocation microstructures can dramatically affect the mechanical performances of metallic alloys. Then deformation mechanisms and physical properties must... -
Incommensurate-commensurate phase transitions in K2SeO4
Materials with incommensurate structures often show exotic properties (such as charge density waves). The development of reliable and efficient refinement techniques for such... -
Adsorption Structures of Organics additives at the Iron/Oil Interface and the...
Numerous chemical additives have been added to steel surfaces to improve adhesion, and prohibit corrosion if the substrate is reactive to its surrounding environs. This... -
quenching and partitioning the new heat-treatment process 44
quenching and partitioning the new heat-treatment process 44 -
Startup and Calibration
This dataset has no description
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Assembling floating, very sparsely tethered, protein-lipid bilayers.
We have recently used Polref in to measure the assembly of tethered floating lipid bilayers. These are useful models of biological membranes in which a phospholipid bilayer is... -
pH Responsive Polymer Blend Surfaces
Polymers, end-functionalised with carboxylic acid (COOH) groups do not normally segregate to film surfaces due to the high surface energy of these functionalities. However, we... -
Tuneable Adsorption of Soft Colloids on Model Biomembrane
Understanding how nanoparticles interact with lipid bilayers will potentially have high impact on the development of new drug delivery systems, and on the investigation of their...
