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SANS Investigation on Packing Structure of Proteasome Activator 28
Proteasome plays an important role in the processing of antigenenic proteins for presentation by the MHC class I pathway. PA28 is an activator of the 20S proteasome, a large... -
Micellization in glycerol:choline chloride deep eutectic solvent
Deep Eutectic Solvents (DES) are molecular mixtures with melting points below room temperature. DES share many features of ionic liquids (low vapour pressure, adjustable... -
Using SANS to understand the structure and behaviour of surfactants in chocolate
Molten chocolate is a semi-solid suspension of (mostly) sugar, but also cocoa and milk solids in oil. In order to allow the sugar grains to flow past each other, either when the... -
SANS studies of Amphotec (aggregates of amphotericin-cholesteryl sulfate)
The anti-fungal agent amphotericin B (AmB) can be administered to patients in aqueous solution complexed with cholesteryl sulfate (CS), and this formulation helps to minimise... -
Coordinated, Recoiling Molecules Tethered by Hydrogen Bonding: Ammonia in Zeo...
We request 5 days on IRIS to investigate the hindrance to molecular rotation of ammonia in a zeolite framework due to hydrogen bonding interactions. This is a tied proposal to... -
Revealing the Structure behind the Synergistic Phase Behavior of the Ternary ...
The aim of this collaborative proposal is to unravel micro- and nano-structures underlying unusually high solution viscosities from mixed surfactant systems. SANS is a unique... -
Probing membrane localisation of molecular rotors (SANS)
A number of important biological processes, such as intracellular transport and signal transduction depend on the viscosity and the distribution of microdomains in cells. We... -
Nanoscale Phase Separation in Organic Solar Cells and Its Impact on Device Pe...
Solid-state Organic Solar cells (OSCs) have the potential to be the basis of a renewable energy source that is inexpensive and portable. Current state-of-the-art... -
Phase Separation in Organic Photovoltaic Cells
Organic photovoltaic (OPV) cells have the potential to be the basis of a renewable energy source that is inexpensive and portable. Current state-of-the-art solution-processed... -
The solution structure of the OmpF¿Colicin N complex in neutral detergent by ...
Gram negative bacteria cause a wide range of diseases including meningitis, bubonic plague, gonorrhoea, diarrhoea, Legionnaires' disease and cholera. Their outer membrane... -
Aggregation behaviour of aqueous hairy rod conjugated polyelectrolyte/surfact...
Small angle neutron scattering (SANS) will be used to characterise the structures of aggregates formed between the anionic conjugated polyelectrolyte... -
SANS from photoconductive hydrogel mixtures and their gelators.
Hydrogels are formed from a self?assembled network of fibres made up of small molecules (gelators) trap and hold water at just 1% by weight, or less, from the solution they are... -
Non-equilibrium kinetics in highly interacting polymer mixtures
We seek to investigate the non-equilibrium phenomena of a model polymer mixture by time-solved SANS and temperature jump experiments within (a) one-phase region and (b) one to... -
Building a model for gastric mucins
Gastric mucus is a vital component for the protection of the stomach from the highly acidic gastric secretions, preventing autodigestion and providing mechanical protection.... -
Silk fibrillogenesis: Morphology, structure and hydration of the intermediate...
At the heart of protein¿s aggregation are specific molecular events; and how they are modulated by changes in solvent conditions is key to our understanding and control of...
