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Investigation of PVC plasticizers on phospholipid monolayers
Plastic bags are used as containers for storage of donated blood. These bags are typically made out of PVC plasticized with dialkylphthalates (e.g. DEHP), which migrates into... -
Investigation of surface conjugation of proteins in lipid membrane using neut...
Bilayer lipid membranes and their interactions with the integral or peripheral proteins serve as one of the key mechanism in various cellular functions like communication, cell... -
How N-acyl amino acid surfactants adsorption at the air/water interface helps...
N-acyl amino acids are promising anionic amphiphilic molecules, which consist of a linear aliphatic chain (hydrophobic tail) and an amino-acid residue (polar head). Although... -
Adsorption of Therapeutic Monoclonal Antibodies at the Air/liquid Interface b...
The air/water interface works as the simplest model for screening protein adsorption. Many previous studies have been made to examine protein adsorption at this interface.... -
Lipopolysaccharide Functions as Bacterial Receptors to Antimicrobial Peptides
Neutron reflection (NR) is well established for studying molecular films such as lipid monolayers. Its high depth resolution combined with deuterium labelling can determine the... -
Lipodepsipeptides and Brown Blotch Disease in Mushrooms (ii) the role of tola...
Tolaasin is a lipodepsipeptide (lipo = hydrophobic side chain, depsipeptide is an amino acid ring closed in a particular way) produced by strains of Pseudomonas tolaasii, and it... -
Study of mixed biopolymers at the oil-water interface
Proteins are important in many applications ranging from the stabilisation of emulsions (oil-water interface) to foams (air-water interface). Understanding the relationship... -
Steroidal drug containing dodecyl sulphate monolayers: effect of counterion
An number of potential drugs, including steroidal drugs are extremely water insoluble, limiting their commercialisation as medicines. Solubilisation of drug in surfactant... -
Effect of polar solvent on the structure of monolayers of phospholipid
It is the aim of the proposal is to perform neutron reflectivity (NR) studies combined with contrast variation to determine the structure of phospholipid monolayers on a... -
Tuneable Creation of Reservoir Structures at the Air/Water Interface
Recently we have exploited non-equilibrium effects in the preparation of super-efficient polyelectrolyte/surfactant films at the air/water interface spread from the dissociation... -
Mixed Amino-Acid Based Surfactant Monolayers
Amino acid based surfactants have been known for many years but so far few detailed studies have been carried out on their properties. We are using amino acids extracted from... -
Protein nanosheets assembled structures at the air-water interfaces for cell ...
Cell adhesion and proliferation at the surface of liquids such as oil droplets is a surprising phenomenon as it is typically accepted in the field of bioengineering that cells... -
Autoxidation vs. Ozonolysis of Surfactant Mixtures Containing Poly-unsaturate...
Surface-active molecules with water-loving and water-hating parts have been found to contribute substantially to the man-made urban aerosol load originating from cooking... -
The Effect of Temperature on the Formation of Surfactant-Metal Ion Multilayer...
We have now established that multilayering at the air-water interface is a widespread phenomenon brought about by multivalent ions, whether polyelectrolyte, oligoelectrolyte or... -
Structures of cardiolipin-bound cytochrome c in pathological conditions
Cardiolipin (CL) is a structurally unique dimeric phospholipid localized in the inner mitochondrial membrane, which is known to provide essential structural and functional... -
Antimicrobial Mechanisms of Model Biocides via Their Interaction with Lipopol...
The global increase of bacterial resistance to antibiotics has led to increasing interest in research focusing on the development and characterization of new antimicrobial... -
Neutron reflectivity studies of the interaction between a novel antimicrobial...
A Unilever proprietary technology has been shown to inhibit biofilm growth and development, and is also found to possess antimicrobial activity, effective both as a... -
Interaction of Surfactant with Model Lipid Membranes: Influence of Surfactant...
Skin becomes a target of drug delivery because the transdermal routes are non-invasive, can be self-administrated, improve patient compliance and can provide release for long... -
Interactions of de Novo Designed Antimicrobial Lipopeptides with Model Leafle...
In this work, we propose to exploit the unique capability of neutron reflection (NR) to study the structural changes of multi-component lipid monolayer models mimicking... -
More than the sum - oxidation behaviour of mixed fatty acid monolayers
Single molecule thin films of various surface-active species are found on the surface of water bodies from the sea down to microscopic spray droplets. These films affect the...
