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Neutron reflection study of spin coat grapheme oxide films
We have recently been able to form a thin graphene oxide (GO) film with uniform thickness around 30±2Å from aqueous GO suspensions by spin coating (onto small wafers for... -
The mechanism of lipid transport in Gram-negative bacteria
The bacterial cell envelope is one of the best targets for antimicrobial development. It is this envelope that harbours the instruments of microbial warfare, preventing its... -
INTERACTIONS OF PAMAM DENDRIMERS WITH DESIGNER BIOSURFACTANTS AT THE SOLID/LI...
Poly(amidoamine) (PAMAM) dendrimers have been identified as potential gene vectors. We have studied their association with surfactants, dilauroylphospholiponucleosides (DLPN),... -
Determination of kinetics of adsorption and layer thickness of lamellar gel s...
The phase behaviour of aqueous surfactant systems and in particular the transition between a gel (Lb) and liquid crystalline (La) phase can be influenced by some low molecular... -
Surfactant mixing at hydrophilic solid/liquid interfaces: (A) air/water measu...
The overall objective is to model the amount and composition of adsorbed mixtures of three types of zwitterionic surfactant and two charged surfactants at the silica/water... -
Neutron Reflectivity Study of Protein Adsorption onto Cell Membrane-inspired ...
We grafted 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer brush from the silicon wafer surface through Cu (0) mediated controlled radical polymerization (CuCRP) to mimic... -
Lipopolysaccharide Functions as Bacterial Receptors to Antimicrobial Peptides
Neutron reflection (NR) is well established for studying molecular films such as lipid monolayers. Its high depth resolution combined with deuterium labelling can determine the... -
The Orientation and Conformation of Synthetic 3-10 Helical Peptides within Su...
This dataset has no description
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Neutron Reflection from a Biomineralisation Glycosaminoglycan on Calcite
Here we aim to structurally characterise the formation of adsorbed monolayers of heparin on calcite to address how these species influence biomineralisation and the inhibition... -
Organization of mitochondrial membranes upon oxidative stress: Impact on apop...
Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). The mitochondrial apoptotic pathway is a... -
Novel block bottlebrush polyelectrolytes: The effect of cationic block charge...
In this work we will study a novel block copolymers consisting of a linear cationic block and uncharged bottle-brush block having 45 units long poly(ethylene oxide) side chains.... -
The Orientation and Conformation of an Enantiomeric Pair of 310 Helical Pepti...
We wish to investigate the interactions between peptide mimics of peptaibols, a highly active class of natural antimicrobial peptide, and membranes. In particular we are... -
Assessing the interactions of cyclic peptide-polymer conjugates with a lipid ...
Cyclic peptide-polymer nanotubes can readily self-assembly into long nanotubes, and are being extensively studied for drug delivery applications. As such, understanding how... -
Effect of alkyl chain length on the adsorption of n-alkyl phosphocholine surf...
This proposal relates to the study of adsorption of n-dodecyl phosphocholine (C12PC) at the oil-water interface. The thickness of the adsorbed monolayers measured for dC12hPC... -
Interactions between Designed Antimicrobial Lipopeptides and Inner Membrane L...
Neutron reflection will be used to reveal the structural changes from different inner membrane leaflet models upon interacting with a group of antimicrobial lipopeptides with... -
The effect of bilayer rigidity on the interactions with perfluoroalkyl compounds
Perfluoroalkyl substances (PFASs) are used extensively in industrial products although have been identified as emerging pollutants accumulating in wildlife and environment.... -
Adsorption of proteins from Moringa seeds at the air/solution interface
Proteins from Moringa trees have attracted considerable interest as flocculents for water purification and possibly as materials for remediation of contaminated soil.... -
Interaction of human dihydroorotate dehydrogenase with ubiquinone in model li...
Human dihydroorotate dehydrogenase (DHODH) is a membrane-bound enzyme of clinical interest and a well-validated drug target for e.g. rheumatoid arthritis and multiple sclerosis.... -
Neutron reflection study of effects of non-ionic alkyl ethoxylates on model w...
We propose to use NR to study the structural features of the model wheat wax films formulated from the known main components of long chain primary alcohols and an ester. By... -
Quantifying the Asymmetry in Cell Membrane Mimetic Supported Lipid Bilayers.
Cell membranes are characterised by complex lipid composition and asymmetric distribution of lipids (lipids facing the outside of the cell are different from the lipids that are...
