297 datasets found

The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the...

The Gram negative bacterial outer membrane protects the bacterium from toxins such as antibiotics and is partially responsible for the rapid rise in antibiotic resistance in...

The reliability of combustion engines is enhanced by lubrication, which provides wear protection along with reduced emissions and fuel consumption through the minimisation of...

The Earth's climate is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects droplet size and optical properties, important effects. Common...

Silicon electrodes for Li-batteries have a ten times higher gravimetric energy density than current electrodes. The major drawback is the big capacity fading associated with the...

Salivary films are (mostly) proteinaceous nm-thick films that form on any type of surface upon exposure to saliva. The role of the pellicle is manifold. Among its functions,...

Purothionins and defensins are basic, amphiphilic, cysteine-rich and low molecular weight plant defence proteins. These proteins are active against a broad range of...

Biological membranes do not only occur as planar bilayer structures, but bilayers have also been shown to, depending onthe lipid composition, curve into intriguing 3D...

The crystallisation of membrane proteins is of great interest, not least, to the pharmaceutical industry. We have recently begun a project aiming to investigate the role played...

The outer membrane (OM) of Gram-Negative bacteria (GNB) is an asymmetric structure which contains complex lipids known as lipopolysaccharides (LPSs) on the outer surface. LPSs...

The very heterogeneous, but non-random, arrangement of lipids and proteins in cell membranes, known as rafts are of major scientific interest. Lipids in cell membranes are...

Pore forming lipopeptides, such as Tolaasin, are produced by pathogenic mushroom bacteria, and are implicated in diseases such as ¿brown blotch¿ disease. They have potential...

Oxidation of lipid membranes is widely known to play a crucial role in many cellular processes and pathological conditions such as apoptosis, inflammation, infection, or sepsis,...

Many drugs are both poorly water-soluble (hydrophobic) and lipophilic in nature and are therefore incorporated into surfactant micelles and monolayers. As the incorporation of...

DNA is a versatile building material for nanotechnology. We have recently studied a surface-tethered single-domain DNA motor by neutron reflection (IR) for the first time. We...

Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce...

An increasing number of potential drug molecules are extremely water insoluble, limiting their commercialisation as medicines. Solubilisation of drug in surfactant micelles is a...

Foam stability, appearance and functionality is governed by the thin liquid films between foam bubbles. These films are stabilised by surface active molecules (surfactants and...

Cell membrane being the first line of defence of a complex cell, it forms an important scientific topic to study its encounter with various external entities. Nanoparticles are...

In this proposal, we request beamtime to study the unexpected behaviour of a strongly bound bilayer of the cationic surfactant didodecyldimethylammonium bromide on the anionic...