Pore forming lipopeptides, such as Tolaasin, are produced by pathogenic mushroom bacteria, and are implicated in diseases such as ¿brown blotch¿ disease. They have potential applications as anti-fungal, anti-bacterial, anti-viral molecules, and as anti-cancer agents. Biogenic agents, such as octopamine, are observed to enhance or suppress biofilm formation in the tolassin expressing bacteria, such as Pseudomonas fluorescens, with significant bio-medical implications. We propose to use NR to investigate the surface adsorption properties of tolaasin in the presence of octopamine, in order to understand the role of their surface adsorption and interaction on the mechanism of tolaasin biofilm control.