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Salt effects on gelation of oxidised cellulose nanofibrils with nonionic surf...
Our group has been studying partially oxidised anionic cellulose (AC) nanofibrils which form gels in the presence of moderate salt concentrations and with anionic surfactants.... -
Di-chain sulfobetaine monolayers at the air-solution interface
Here we wish to continue our investigation of sulfobetaine surfactants in which the charges on the zwitterionic headgroup are reversed compared to those on zwitterionic... -
Phase behaviour of di and triblock eGFP-copolymer conjugates in aqueous media
Conjugation of therapeutic proteins to polymers is well established but most methods result in multi-site and multiple conjugation or crosslinking resulting in lack of... -
Encapsulation of monomers in cationic surfactant-polymer films
We have been studying the formation of solid polymer-surfactant films at the air-solution interface formed from cationic surfactants with PEI. We wish to use the highly... -
Encapsulation of Hydrophobic Species in Surfactant Micelles
Our recent work demonstrates that the details of water structure around micelles are now accessible using Empirical Potential Structure Refinement methods combined with neutron... -
Micelles in Deep Eutectic Solvents
Deep Eutectic Solvents (DES) are molecular mixtures similar to ionic liquids, having melting points below room temperature. However instead of being composed of a salt, the... -
Linking solvent structure to materials synthesis: Choline Chloride:Urea-Water...
Deep Eutectic Solvents (DES) are formed by complexing appropriate organic salts and neutral hydrogen bond donor species to produce chemically tuneable, low volatility liquids... -
Polymer-Lipid Nanodisc Adsorption to the Air-Solution Interface
Nanodiscs are self-assembled structures composed of phospholipids containing a stabilizing membrane-scaffold protein or, in the case of this proposal, a polymer belt. They are... -
Sulfobetaine monolayers at the air-solution interface: response to cation bin...
Binding of divalent ions to zwitterionic phospholipids in monolayers and bilayers has been widely studied due to the obvious relevance of these systems to cell membranes and... -
Alcohols in Cationic Surfactant Micelle Solutions
This proposal continues our studies of water and small molecule binding around surfactant micelles using NIMROD, to obtain previously inaccessible details of their molecular... -
Salt Effects on Self-assembly of Polyoxometallate Surfactants in Aqueous Solu...
This proposal continues our work on polyoxometallates (POM)-headed surfactants. POMs are well defined transition metal clusters with a range of interesting catalytic, magnetic... -
Counterion binding to nonionic micelles: effect on interactions with silica
This proposal continues our research on ion binding to surfactant micelles. Our recent work demonstrates that the details of water structure around micelles are now accessible... -
Growth of Nanostructured Ceria in Choline Chloride:Urea-Water Deep Eutectic S...
In our recent work we have studied formation of nanostructured cerium oxides from the choline chloride:urea deep eutectic solvent (DES). We found that the nanostructure of the... -
Neutron reflectivity study of phase separation in polymer-drug thin films
Nearly 40% of new chemical entries are poorly water-soluble. Drug encapsulation into water-soluble polymers is an active research area owing to the ability of improving drug... -
Effects of curvature and temperature on structure of lipid-polymer nanodiscs
Nanostructured lipid aggregates offer enormous potential as tools for membrane structural biology and biophysics. Styrene-Maleic Acid Lipid Particles have a number of attractive... -
Encapsulation of hydrophobic species in mixed micelles in polymer solutions
This proposal continues our investigations into film-forming polyelectrolyte-surfactant solutions. We have found that mixed micelle systems offer greater control over micelle... -
Zwitterionic Polymers for Lipid Nanodisc Stabilisation
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using... -
Morphology and Phase Diagram of Thermoresponsive Polymer-Protein Conjugates
Using an enzyme mediated conjugation method we have prepared well-designed protein-polymer conjugates using a model protein, green fluorescent protein (GFP) with... -
Applying self-assembly in deep eutectic solvents to templated ionothermal syn...
Deep Eutectic Solvents (DES) are a subclass of room temperature ionic liquids (ILs). They are mixtures of an organic salt with a hydrogen bond donor that form strong... -
Growth of silica-surfactant particles during surfactant-templated silica synt...
Surfactant templated silicates are formed by the polymerization of silica around surfactant micelles in solution. Our previous SANS experiments show development of the initial...