158 datasets found

Nanostructured lipid aggregates offer enormous potential as tools for membrane structural biology and biophysics. Styrene-Maleic Acid Lipid Particles have a number of attractive...

Amino acid based surfactants have been known for many years, but so far few detailed studies have been carried out on their properties. We are using amino acids extracted from...

Our recent work demonstrates that the details of water structure around micelles are now accessible using Empirical Potential Structure Refinement methods combined with neutron...

This proposal continues our investigations into polyelectrolyte-surfactant thin films which form at the air-solution interface. Our previous work investigated structure...

Amino acid based surfactants have been known for many years but so far few detailed studies have been carried out on their properties. We are using amino acids extracted from...

Deep eutectic solvents (DES) share many features with ionic liquids (ie. tunable physicochemical properties) which makes them viable green solvents that are less toxic than...

Nanodiscs are self-assembled structures composed of phospholipids stabilised by a polymer belt. They are capable of encapsulating single membrane proteins and as such have many...

We have observed formation of polymer-surfactant films at the air interface having a range of structures, related to their solution interactions. The films form with...

Clarithromycin and Levofloxacin are essential antibiotics used to treat bacterial infections such as tuberculosis and pneumonia. Lung surfactants may be used as drug carrier of...

We are currently investigating phenylboronic acid modified polyacrylamides with variable phenylboronic acid block lengths as a route to glucose sensors with controllable...

Recently we have trialled the new techniques enabled on Larmor which permit simultaneous measurements of nanoscale and macroscale structure. These experiments gave new insights...

Deep eutectic solvents (DES) are mixtures of organic salts and hydrogen bond donors, that form strongly hydrogen-bonded room temperature liquids. DES share many features with...

Our group has been working partially oxidized cellulose nanofibrils which form gels in aqueous formulations. Recently we have observed that these fibrils also gel when dialysed...

Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies and biophysics. Previously we have studied nanodisc...

Our group has been studying partially oxidised anionic cellulose (AC) nanofibrils which form gels in the presence of moderate salt concentrations and with anionic surfactants....

Nanodiscs are self-assembled structures composed of phospholipids containing a stabilizing membrane-scaffold protein or, in the case of this proposal, a polymer belt. They are...

In this proposal we wish to continue our recent work using polyelectrolyte-surfactant films as templates for inorganic structures, in this case titania....

Dye sensitised solar cells, based around colloids of the wide bandgap semiconductor TiO2 with bound dyes have potential to provide a cheap,sustainable source of solar energy...

The development of styrene-maleic acid lipid particles (SMALP) is opening the door to better understanding the nature of membrane proteins, these particles have been well...

We have been developing hydroxypropylmethyl cellulose (HPMC) microspheres for delivering poorly water-soluble drugs. The in vitro dissolution data showed that the presence of...