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Investigation of phosphatidylcholine and its interaction with 1,2 propandiol ...
The aim of the present study is to use neutron diffraction enhanced with isotopic substitution and subsequent computer simulations to determine the head group solvation of a... -
Understanding the interfacial behaviour of bile salts to better engineer lipi...
The current project aims to 1) elucidate how bile salts (BS) structure influences their interfacial behaviour and role during lipolysis; 2) to study the potential ability of... -
Peptide resistance in asymmetric MRSA-mimetic vesicles
We have been investigating the influcence of the cationic staphylococcal lipid lysyl-phosphatidylglycerol (L-PG) on bacterial resistance to antimicrobial peptides (AMPs). Using... -
Interfacial properties of semiconducting polymer nanospheres for in vivo imaging
Semiconducting polymer nanospheres (SPNs) show potential as non-toxic agents for bio-imaging. They are formed from mixtures of hydrophobic fluorescent polymers and... -
Lipopolysaccharide-antimicrobial peptide complexes in solution:elucidation of...
Lipopolysaccharide or endotoxin (LPS) is an amphiphilic macromolecule which constitutes the outer membrane of gram negative bacteria.During infection, LPS is released from the... -
Understanding the interfacial behaviour of bile salts to better engineer lipi...
The current project aims at elucidating how bile salts (BS) structure influences their interfacial behaviour and their impact on fat digestion. Neutron reflectivity (NR) is the... -
Understanding Surfactant-Semiconducting Polymer Interactions for Optimisation...
This dataset has no description
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A biophysical approach of studying the molecular interactions of a novel anti...
Gram negative (-ve) bacteria possess numerous defenses against antibiotics, not the least of them being the intrinsic permeability barrier afforded by their outer membrane (OM)... -
Neutron Reflectivity Study of Antimicrobial Peptides Interacting with Lipopol...
The outer membrane (OM) of gram negative bacteria is mainly constituted of highly polydisperse and amphiphilic lipopolysaccharide (LPS), an endotoxin which is accompanied by... -
Small angle neutron scattering study on the interaction between antimicrobial...
Bacterial endotoxins, or lipopolysaccharide (LPS), released from the gram negative bacterial membrane, form different aggregates in solution which morphology depends on the type... -
Understanding the interfacial behaviour of bile salts to better engineer lipi...
The current project aims at elucidating how bile salts (BS) structure influences their interfacial behaviour and their impact on fat digestion. Neutron reflectivity (NR) is the... -
Interpreting the Effect of Small Ions on Charged Lipid Membranes
We propose a study to extend the understanding of the influence of salt on the structure of DPPG membranes floating on an al-PC bilayer. We have previously demonstrated the... -
Characterisation and peptide resistance capabilities of bacterial membrane mi...
Lysylphosphatidylglycerol (LPG) is a major constituent of the plasma membrane of the bacterial pathogen methicilin resistant Staphylococcus aureus (MRSA), which has been... -
Aggregate structures formed by lipopolysaccharide-peptide complexes in solution
Bacterial lipopolysaccharide (LPS) is a bioactive structural amphiphilic molecule which forms the outer leaflet of the outer membrane of the Gram negative cell envelope. During... -
Understanding Surfactant-Semiconducting Polymer Interactions for Optimisation...
This dataset has no description
