Nimrod is a unique instrument that bridges atomic resolution solution scattering with small angle scattering. The opportunity therefore exists to probe both the microscopic interactions between protein and solvent and solute at atomic resolution, and also to examine in detail the repulsive or attractive interactions between proteins in the same experiment. This offers us an unprecedented opportunity to take a unified approach that will enable us to begin to unravel the details of protein-solvent and protein-protein interactions across this range of length scales.We will exploit the capacity of the Nimrod instrument to examine the interactions between lysozyme, a small model protein, and aqueous solvents containing a range of salts, as a function of protein and of salt concentration.