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The search for ALC resonances in TRP-TYR: pioneering spatial and temporal res...
Electron transfer (ET) processes in peptides and proteins are key steps in the functioning of several natural enzymes including DNA photolyase and ribonucleitide reductase,... -
Interaction of polypeptide with surfactant on the surface of water
This proposal constitutes part of our ongoing study towards understanding the adsorption of collagen based polypeptide and its interaction with ionic surfactants at the... -
Modelling Protein-Protein Interactions and the Hofmeister Effect
Nimrod is a unique instrument that bridges atomic resolution solution scattering with small angle scattering. The opportunity therefore exists to probe both the microscopic... -
Temperature and environment dependence of the isotope effect in muonated radi...
We plan to measure the hyperfine constants for both the muon and the equivalent hydrogen atom in a small muonated radical using time-differential ALC. We will follow this as a... -
Stabilising emulsions with protein-surfactant mixtures.
Hydrophobins, hfb2, are secreted fungal proteins, which are strongly surface active and possess powerful emulsion and foam stabilising properties. Understanding their... -
Insertion of antimicrobial peptides into phospholipid monolayers at air/liqui...
We have designed a series of cationic peptides with different helix repeats that can kill bacteria but remain benign to mammalian host cells. The selectivity to cell types is... -
Using SERGIS, SESANS and NR to probe nanoscale cavities created within templa...
Nanoporous membranes fabricated by polymerization around soluble templates have found many applications in (bio)sensors, charge storage devices, filtration and catalysis.... -
Recreating the specific colicin NRa-LPS interaction in a model bacterial out...
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
SANS Study of the interaction of model wax alcohols with non-ionic surfactant...
The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving... -
Probing the viability of water-in-CO2 microemulsions with Headgroup-free amph...
Recent SANS studies of an unusual headgroup-free surfactant (Nohead FC6-HC4) produced data that implied the formation of W/CO2 microemulsions (MEs) at a particular pressure (P)... -
Impact of multivalent counterions on surfactant self-assembly
We request SANS beam time on LOQ to study the impact of multivalent counterions on the micellisation of alkyloxyethylene sulfate surfactants and alkyloxyethylene sulphate /... -
Electrolyte induced self-assembly of methyl ester sulphonate surfactants
The addition of multivalent counterions (Al3+, Mg2+) induces multilayer adsorption of ionic surfactants at interfaces. It is associated with strong wetting conditions, invoking... -
Revealing the Structure behind the Synergistic Phase Behavior of the Ternary ...
The aim of this collaborative proposal is to unravel micro- and nano-structures underlying unusually high solution viscosities from mixed surfactant systems. SANS is a unique... -
Validating a new theoretical method for predicting the HFC of small molecular...
ALC is the best technique to characterize muoniated radicals, that are produced by muonium bonding to unsaturated bonds in molecules. Good agreement between data from ALC and... -
Adsorption maxima at the solid/liquid interface
Adsorption maxima have been reported for adsorption at the hydrophilic solid/water interface based on measurements on powders and solution analysis. Many would claim that this... -
Interfacial layer structure of lipopeptides adsorbed at the air/water interface
Lipopeptide surfactants are a group of interesting biosurfactants due to their natural origin and their high effectiveness at reducing interfacial tension. However, there is a... -
Interaction of polypeptide with surfactant on the surface of water
This proposal constitutes part of our ongoing study towards understanding the adsorption of collagen based polypeptide and its interaction with ionic surfactants at the... -
Floating Bilayer Mimics of the Gram Negative Bacterial Outer Membrane
The gram-negative bacterial membrane is of extreme medical importance. The two main lipid components of the outer membrane are lipopolysaccharides (LPS's) and DOPE. We will... -
Calcium mediated interaction between siRNA and phospholipid bilayers: the eff...
The main objective of the present study is to gain an understanding of the nature of the interaction of ¿phospholipid membranes¿ with small, interfering RNA (siRNA) in the... -
Benchmarking improvements in experimental design in neutron reflectometry
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