The 3D chirality of malaria parasites determines their motion patterns in 2D and originates at the apical pole [data]

DOI

This is a data repository for the upcoming publication "The 3D chirality of malaria parasites determines their motion patterns in 2D and originates at the apical pole". It includes example data for the different experimental setups, which can be used to run the analysis code. The code is available in the git repository github.com/LeonLettermann/hei-sporo-code and therein linked repositories.

We present data for three different experiments here:

3D microscopy of sporozoites moving through hydrogels
Two-sided traction force of circling sporozoites
STED super-resolution microscopy of sporozoites underneath a hydrogel

For experiments 1 and 2, the data are presented as .mvd2 microscopy raw data, which can be opened and analyzed with the provided Python code. For experiment 3, we present a deconvoluted image as a .tif file. Additionally, different intermediate analysis results supporting experimentation with the provided code are available as .npy files.

Identifier
DOI https://doi.org/10.11588/DATA/4YBYXE
Metadata Access https://heidata.uni-heidelberg.de/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.11588/DATA/4YBYXE
Provenance
Creator Lettermann, Leon ORCID logo; Singer, Mirko ORCID logo; Steinbrück, Smilla; Ziebert, Falko ORCID logo; Kanatani, Sachie ORCID logo; Sinnis, Photini ORCID logo; Frischknecht, Friedrich ORCID logo; Schwarz, Ulrich S. (ORCID: 0000-0003-1483-640X)
Publisher heiDATA
Contributor Lettermann, Leon
Publication Year 2025
Funding Reference German Research Foundation P.-Nr.: 492010213 ; German Research Foundation P.-Nr.: 240245660 ; bwFor and German Research Foundation INST 35/1597-1 FUGG ; Ministry of Science, Research and the Arts Baden-Württemberg (MWK) and German Research Foundation INST 35/1503-1 FUGG
Rights CC BY 4.0; info:eu-repo/semantics/openAccess; http://creativecommons.org/licenses/by/4.0
OpenAccess true
Contact Lettermann, Leon (Heidelberg university, ITP & Bioquant)
Representation
Resource Type Dataset
Format application/zip; text/plain
Size 12717974007; 957; 20939; 3869343763
Version 1.0
Discipline Basic Biological and Medical Research; Biology; Biophysics; Life Sciences; Medicine; Natural Sciences; Physics