Decoding stimulus-specific regulation of promoter activity of p53 target genes - Data and analysis code

All measurements derived from smFISH experiments as well as additional output from Bayesian inference are publicly available via the institutional repository of Technical University Darmstadt. This includes separate plots of the parameters (f, µ, δ) for each gene and condition with corresponding confidence intervals, histogram fits of the active TS exon fluorescence data, histogram fits of the RNA counts, plots of MCMC convergence, posterior distributions of the parameters inference and fitting of TS quantification. Raw image data are available from the corresponding authors upon reasonable request due to their large size. The corresponding analysis code is available as well.

Identifier
Source https://tudatalib.ulb.tu-darmstadt.de/handle/tudatalib/4520.2
Metadata Access https://tudatalib.ulb.tu-darmstadt.de/oai/openairedata?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:tudatalib.ulb.tu-darmstadt.de:tudatalib/4520.2
Provenance
Creator Vigliotti, Flavia; Engelmann, Nicolai; Szinger-D'Angelo, Mark; Koeppl, Heinz; Loewer, Alexander
Publisher TU Darmstadt
Contributor TU Darmstadt
Publication Year 2025
Rights Creative Commons Attribution 4.0; info:eu-repo/semantics/openAccess
OpenAccess true
Contact https://tudatalib.ulb.tu-darmstadt.de/page/contact
Representation
Language English
Resource Type Dataset
Format application/zip; text/plain
Version 1.1
Discipline Other