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Investigation of a novel mechanism of antibiotic resistance
This dataset has no description
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Neutron Reflection Studies on Adsorption of Lauroyl-L-Carnitine (C12-L-Caniti...
Acyl L-Carnitines are a group of novel surfactants with attractive physical and biological properties associated with their head group charge features. This work proposes to use... -
Intra-membrane lipid flipping in model lipid membranes
Lipid compositional variation across the cell's membranes as well as asymmetry between two contiguous monolayers in the same membrane are critical for alive and healthy cells.... -
Investigating the influence of the oxide on adsorption and corrosion of coppe...
Copper is an important industrial metal, predominantly used in electrical wiring and plumbing, as well as in power transformers. Throughout these applications, sulphur is known... -
Neutron diffraction from polyunsaturated multibilayer membranes containing a ...
Polyunsaturated fatty acids (PUFAs) are essential dietary fats that have been proposed to reduce the risk of cardiovascular and auto-immune diseases, arthritis and cancer. PUFA... -
Membrane interactions of virus-like silica nanoparticles as antimicrobial pep...
As a result of an increasing number of bacteria developing resistance against antibiotics, antimicrobial peptides (AMPs) are currently attracting significant interest. However,... -
Probing Ion Binding to Micelles ¿ Investigating the Hofmeister Series
This proposal continues our research on ion binding to surfactant micelles. Our recent work demonstrates that the details of water structure around micelles are now accessible... -
Purothionin binding to model fungal lipid membranes
Purothionins and defensins are basic, amphiphilic, cysteine-rich and low molecular weight plant defence proteins. These proteins are active against a broad range of... -
Model Amphiphilic Deep Eutectic Liquids
Deep eutectic liquids (DELs) - mixtures of high melting-point solids that form stable liquids near room temperature ¿ have recently emerged as a new class of novel solvents with... -
Neutron Diffraction Studies of Vanadium Sulfate Cathode Materials
Vanadium based compounds have attracted considerable interest as positive electrode materials for Li ion batteries. This is due to vanadiums ability to display a range of... -
Interfacial layer structure of designed lipopeptides at the solid/water inter...
Lipopeptide surfactants are a group of interesting biosurfactants due to their natural origin and their high effectiveness at reducing interfacial tension. However, there is a... -
A study of the role of divalent cations in the stability of smooth LPS in out...
The Outer Membrane (OM) is found in bacteria which cause plague, cholera & Legionnaires disease. It is important as; a barrier to antibiotics & the site of... -
CRISP ACCESS FOR NON-COLLINEAR MAGNETISM
The Superconducting Ferromagnetic Metamaterials (SFM) consortium -
Lipid exchange between high density lipoprotein (HDL) and model phosphatidylc...
Lipoproteins are the main carriers of lipids in the body. HDL is believed to favor cholesterol removal and decrease the risk to develop atherosclerosis and related... -
Magnetic contrast NR to resolve MscL opening under PXG challenge
In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock, but, as with all ion channels, they have the potential to act as an Achilles heel,... -
Modelling the Intracellular Lipid Shuttling Mechanism of Non Specific Lipid T...
Previously we have examined the interaction of barley non-specific lipid transfer protein (nsLTP1) with OTS and lipid monolayers at the solid/liquid interface. Examining the... -
Structure of Confined Albumin Layers
In the context of a project in collaboration with ISIS that focuses on structural studies under mechanical confinement, with a specific focus on biological lubricants, the... -
Self-assembly of beta-casein and beta-casein / hydrophobin mixtures
Hydrophobins, hfb2, are secreted fungal proteins in the form of a small lipopeptide. They are strongly surface active and self-assemble in solution and at interfaces. They have... -
Neutron reflectivity of water soluble conjugated polymer/surfactant films
Water-soluble conjugated polymers (WSCP) are an important class of materials which have received great attention as active materials in optoelectronic devices and in biosensing.... -
Dynamic P3HT Nanowire Growth in Solution (Sans2d)
We propose to use SANS to probe the self organised formation of P3HT nanowires in a solution of deuterated chlorobenzene over a 48 hr period in order to better understand the...
