UT-GPCR005 Fluorescence anisotropy time-series of competition binding between unlabeled ligands of M1 muscarinic acetylcholine receptor and TAMRA labeled UR-MK342

DOI

Fluorescence anisotropy time-series of competition ligand binding between unlabeled competitors of M1 muscarinic acetylcholine receptor and TAMRA labeled UR-MK342. The dataset contains kinetic traces of UR-MK259, UR-SK-75, McN-A-343, UR-SK-59, Scopolamine, Telenzepine, 4-DAMP, Carbachol, Pilocarpine, Clozapine, Pirenzepine, Atropine, Acetylcholine, Trospium, NMS, Arecoline, W84, Xanomeline and LY2119620 in competition with TAMRA labeled muscarinic acetylcholine recepotor fluorescent ligand UR-MK342. The dataset also contains non-linear regression fits of these time-series. Details of experimental setup are given in the related publication.

Identifier
DOI https://datadoi.ee/handle/33/738
Related Identifier https://doi.org/10.1016/j.bcp.2026.117911
Metadata Access https://datadoi.ee/oai/request?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai:datadoi.ee:33/738
Provenance
Creator Laasfeld, Tõnis; Bláhovcová, Hana; Hollo, Kaspar; Rinken, Ago; Veiksina, Santa; Anni Allikalt
Publisher University of Tartu
Publication Year 2026
Rights info:eu-repo/semantics/openAccess; http://creativecommons.org/licenses/by-nc/4.0/
OpenAccess true
Contact University of Tartu
Representation
Language English
Resource Type info:eu-repo/semantics/dataset
Format .pzfx; .xlsx; application/zip; text/plain
Discipline Other