We ask for 3 days of beam time on Inter/SURF to study the adsorption and adlayer characteristics of avidin on Ti surfaces, relevant for biomedical applications, such as implants. Our specific objective is to understand in detail the immobilization isotherms of avidin as a precursor for further manipulation of osteoinduction on the implant surface to enhance bone-implant integration. This, in turn, will help to maximize the binding capacity and biosurface stability and subsequently enhance the cell attachment to medical device surfaces. In conjunction with related studies on non-biofouling surfaces, it will also improve the design of patterned surfaces for a broad range of biomedical and biophysical applications.