Camadas Finas cruises are part of Brazilian programs whose objective is to study the influence of the Amazon River on the surrounding areas as far as the open ocean. Camadas Finas III carried out in 2012 with R/V Nho Cruzeiro do Sul, which was equipped on-board with an Acoustic Doppler Current Profilers (S-ADCP) to collect the two horizontal components of the current along the ship route (for more information, see Araujo et al., 2017). The 2 min Short Term Averaged (STA) files collected were processed with CASCADE (Chaîne Automatisée de Suivi des Courantomètres Acoustiques Doppler Embarqués) software (Kermabon et al., 2018) and made available.