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Structural studies of thermal responsive nanogels at the oil-water interface
It has been shown that gel particles are able to stabilize the oil-water interface and forming emulsions ( the so called "Pickering emulsions"). It has also been shown that... -
Adsorption of Monoclonal Antibodies at the Solid/liquid Interface
We propose to use neutron reflection to study the interfacial adsorption of 2 novel bispecific therapeutic antibodies at the silicon oxide/water interface. To enpower each of... -
Neutron reflection study into the adsorption and penetration of non-ionic alk...
We propose to explore how to use NR to study the structural features of the reconstituted plant wax films, capturing the main structural characteristics. In addition, we propose... -
The Orientation and Conformation of Synthetic 3-10 Helical Peptides within Su...
This dataset has no description
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How does oxidative damage change peptide membrane insertion?
The insertion of peptides and proteins into cell membranes is crucial for the functioning of cells, and also for the functioning of a variety of antibacterial reagents. Cells... -
NR study of binding of short antimicrobial alpha-helix peptides with model li...
In this work we explore how our rationally designed peptide amphiphiles bind onto lipid monolayers using neutron reflection combined with deuterium labelling to the lipids,... -
Insertion of antimicrobial peptides into phospholipid monolayers at air/liqui...
We have designed a series of cationic peptides with different helix repeats that can kill bacteria but remain benign to mammalian host cells. The selectivity to cell types is... -
NR study of surface adsorption of antibodies with and without non-ionic surfa...
Nonionic surfactants usually do not show affinity to proteins and they work via competitive surface and interfacial processes in abinary mixture. However, we show in this work... -
Adsorption of NHE1 intracellular domain on lipid bilayers
Recently the intracellular domain (ICD ) of the Na+/H+ exchanger isoform 1 (NHE1), is a transmembrane protein, has been identified as an intrinsically disordered protein.... -
Model anionic/non ionic surfactant adsoption at the interface below room temp...
An experiment performed on INTER last year found extreme non ideal mixing between C12E8/SLES3 at the air water interface: this feature became more extreme as the temperature... -
Charged nanogels and their ability to penetrate model lipid membranes
Drug delivery through the skin is an important route for administration of therapeutic agents. However, the outermost layer of the skin, the stratum corneum provides a... -
Investigation of PVC plasticizers on phospholipid monolayers
Plastic bags are used as containers for storage of donated blood. These bags are typically made out of PVC plasticized with dialkylphthalates (e.g. DEHP), which migrates into... -
Lipopolysaccharide Functions as Bacterial Receptors to Antimicrobial Peptides
Neutron reflection (NR) is well established for studying molecular films such as lipid monolayers. Its high depth resolution combined with deuterium labelling can determine the... -
Surface composition in the physical developer process for latent fingerprint ...
Physical developer (PD) is a latent fingerprint development technique that is highly effective on paper and related surfaces, notably banknotes. The process exploits a redox... -
Multilayering of Isostearic Methyl Ester Sulphonate at the Air-Aqueous Interf...
Surfactants usually form a single layer of molecules at the surface of water. We have shown that under certain conditions more than one layer may form. in which case the system... -
The Impact of Multivalent Counterions on the Surface Adsorption of the Anioni...
Surface multilayer formation provides great potential for the tuning and optimising surface wetting properties and applications such as lubrication, drug delivery. Normally... -
The effect of bilayer rigidity on the interactions with perfluoroalkyl compounds
Perfluoroalkyl substances (PFASs) are used extensively in industrial products although have been identified as emerging pollutants accumulating in wildlife and environment.... -
pH-control of swelling and charge neutralization of thin hydrogel films
Hydrogels are widely used in biomaterials science, much due to excellent protein resistance, and physicochemical properties similar to biological tissue. Charge neutrality is... -
Structural refinement of new class of thermo-responsive nanogels to optimise ...
Understanding the transport and adsorption dynamics of nanogels at interfaces as a function of structural morphology are of great importance to further their development and... -
Effect of temperature on the structure of model wax films as studied by neutr...
Cuticular wax films protect plants by mediating water and nutrient transport from the environment. Surfactant is a key ingredient in agrisprays that can promote the uptake of...
