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Physiological adaptation of the diatom Pseudo-nitzschia delicatissima under c...
This dataset contains the data used in the manuscript "Physiological adaptation of the diatom Pseudo-nitzschia delicatissima under copper starvation" accepted for publication in... -
Intra-membrane lipid flipping in model lipid membranes
Lipid compositional variation across the cell's membranes as well as asymmetry between two contiguous monolayers in the same membrane are critical for alive and healthy cells.... -
Neutron diffraction from polyunsaturated multibilayer membranes containing a ...
Polyunsaturated fatty acids (PUFAs) are essential dietary fats that have been proposed to reduce the risk of cardiovascular and auto-immune diseases, arthritis and cancer. PUFA... -
The effect of membrane fluidity on the interaction of antimicrobial proteins ...
Protein-lipid\membrane interactions are fundamentally important to biological processes. We have examined the role protein hydrophobicity in protein-membrane interactions... -
Binding of DNA to Model Membranes in the Presence of Ca2+ Ions and a Membrane...
The aim of the present work is to gain an understanding of the interaction of DNA with the phospholipid bilayers. The effect of different forms of DNA, the presence of divalent... -
Neutron reflectivity studies of the interaction of amphotericin with model ce...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin (AmB) has created a demand for novel anti-fungal agents that can circumvent the pathogens¿... -
Self-Organisation of Phospholipids on Au Electrodes
This experiment is part of a programme to study the effect of applied electric fields on the structure of biomimetic films formed at Au electrodes, with emphasis on... -
Conformational changes on interaction of cytochrome c with lipid monolayers.
The main objective of the present work is to gain an understanding of the interaction of the cationic protein, cyt c with anionic lipid membranes. This objective will be... -
Molecular interactions between phospholipid monolayers and dimethylsulphoxide
Neutron reflectivity will be employed to investigate the interaction between dimethylsulphoxide and monomolecular films of phosphatidylcholine. The monolayer will be used as a... -
Investigation of phase diagrams of polysaccharides
This project concerns fundamental and strategically important research underlying the development of new drug delivery vehicles. We propose to sample phase diagram of... -
Water dynamics in porous PTFE membranes for water purification
This is a resubmitted proposal in a new project on water purification by membrane distillation. With this technology liquid water is excluded from passing the separating... -
Neutron Reflectivity study of lipopolysaccharide complexes with lateral domai...
We propose to investigate the role of lateral phase separation on LPS insertion into model membranes and the effects of target membrane structure and composition. A comparison... -
Kinetics of amphotericin B interaction with model human and fungal cell membr...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents. The successful development of... -
Neutron reflectivity study of bacterial lipopolysaccharide interactions with ...
Bacterial LPS (endotoxin) is a key determinant of host/pathogen interactions. We propose to investigate the role of membrane lateral phase separation on LPS insertion into model... -
Understanding anaesthetics: Ethanol partitioning into lipid membranes, effect...
Ethanol plays an important role in the human metabolism. It is in particular known to act as a drug enhancer by increasing trans-membrane permeability, and as an anesthetic.... -
Conformational analysis of subtilin / lipid II binary antibiotic/target membr...
Antibiotic resistance is pathogenic bacteria is a major clinical problem. Resistance to all antibiotiotic classes, currentl yin clinical use, has been reported. By contrast, the... -
Interaction between the bioactive lipopeptide fengycin and lipid membranes
One class of bioactive lipopeptides produced by Bacillus subtilis, fengycin, has strong surfaceactivity and interesting antifungal property with low hemolytic activityTo gain... -
Microdomains in model membranes using contrast variation SANS
In the present proposal small angle neutron scattering will be used in combination with contrast variation as a non-invasive method to detect the presence and size formation of... -
Amyloid β peptide and α-synuclein association at lipidmodel membranes
We plan to investigate the interaction between amyloid proteins and model biomembranes deposited on solid surfaces. The model membranes will be single zwitterionic and mixed... -
Understanding anaesthetics: Ethanol partitioning into lipid membranes, effect...
Ethanol plays an important role in the human metabolism. It is in particular known to act as a drug enhancer by increasing trans-membrane permeability, and as an anesthetic....
