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Surface structure of monolayers formed by novel di- and tri-chain cationic li...
The aim of the present study is to the determine, using specular neutron reflection (SNR), the structure of layers formed by novel tri-chain cationic lipids in combination with... -
CATIONIC POLYMERS AS POTENTIAL GENE DELIVERY AGENTS: EVALUATION OF CONFORMATI...
Bio-responsive polymers hold great promise as delivery vehicles for drugs, peptides and proteins as their chemistry can be tuned to effect a change in physico-chemical... -
Structure of a cationic polyelectrolyte adsorbed at an oppositely charged sur...
Adsorption of a charged polyelectrolyte onto an oppositely charged substrate is important for the understanding of many natural molecular events as well as for the development... -
Encapsulation of monomers in cationic surfactant-polymer films
We have been studying the formation of solid polymer-surfactant films at the air-solution interface formed from cationic surfactants with PEI. We wish to use the highly... -
Conformational changes on interaction of cytochrome c with lipid monolayers.
The main objective of the present work is to gain an understanding of the interaction of the cationic protein, cyt c with anionic lipid membranes. This objective will be... -
Structure of a cationic polyelectrolyte adsorbed at an oppositely charged sur...
Adsorption of a charged polyelectrolyte onto an oppositely charged substrate is important for the understanding of many natural molecular events as well as for the development... -
Aggregation behaviour in solution of cationic conjugated polymers and oligomers
We extend previous work on aggregates formed by cationic conjugated oligomers in water with surfactants and... -
Interaction of a cationic surfactant with rigid oligoanions
The interaction of small polyelectrolytes or oligoions with surfactants appears to follow a model that we have recently established for large polyelectrolytes but the smaller... -
Direct beam_TRANS
This dataset has no description
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Structure of siRNA containing delivery vehicles: effect of serum
Complexes prepared from cationic, dichain lipid (L) vesicles and negatively charged siRNA (R), with and without positively chargely targeting peptides (P) known as LR or LPR... -
Novel block bottlebrush polyelectrolytes: The effect of cationic block charge...
In this work we will study a novel block copolymers consisting of a linear cationic block and uncharged bottle-brush block having 45 units long poly(ethylene oxide) side chains.... -
vibrational spectroscopy of a novel dipalladium(I) hydride displaying dynamic...
Our report of a novel cationic dipalladium(I) hydride in (Angew. Chem. Int. Ed. 2010, 49, 6315) shows a linear Pd-Pd-H core with H-ligand dynamics (solution NMR). Ab-initio MD... -
Encapsulation of monomers in cationic surfactant-polymer solutions
We have been studying the solution interactions leading to formation of solid polymer-surfactant films at the air-solution interface. We wish to use the mesostructures in the... -
Interactions between a mixture containing two cationic polyelectrolytes and a...
Recently there has been a vast expansion in understanding about the interactions between oppositely charged polyelectrolyte/surfactant mixtures. The use of neutron reflectometry... -
Planar bilayer formation on novel cationic surface suitable for membrane prot...
Membrane receptor proteins (MRPs) which are thought to represent the majority of drug targets are challenging to study as their structure and function is dependent on being... -
Validating calorimetric self aggregation models: Self aggregation of cationic...
Ligand self aggregation is a common problem when studying interactions with bio(macro)molecules. In particular for techniques requiring relatively high ligand concentrations,... -
Curvature effects in polyelectrolyte-surfactant solution interactions
This proposal continues our investigations into polyelectrolyte-surfactant solutions which form thin films at the air-solution interface. Our previous work has investigated the... -
Probing the kinetics of the formation of lipid, peptide and DNA/siRNA complex...
Complexes prepared from cationic, dichain lipid (L) vesicles, positively chargely targeting peptides (P) and negatively charged DNA (D) or siRNA (R), known as LPDs and LPRs... -
Effect of serum on the structure of gene delivery vehicles
To date complexes prepared from vesicles composed of dichain, cationic lipids (L) with negatively charged DNA (D), known as LD complexes have emerged as one of the major... -
The Interaction of Ammonia with Binary and Ternary Deuterides;
The interaction of ammonia with binary hydrides (prototypically, the interaction of LiH with ammonia gas) is thought to be the predominant interaction for hydrogen production...
