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Structure of antibiotic mixtures in lung surfactant membrane models at the ai...
Clarithromycin and Levofloxacin are essential antibiotics used to treat bacterial infections such as tuberculosis and pneumonia. Lung surfactants may be used as drug carrier of... -
Further Studies on the Gating Mechanism of an Antimicrobial Peptide Using Con...
Antibiotic peptides are generally small, simple, usually alpha-helical peptides, which nevertheless show quite complex biological behaviour. We have been studying the gating... -
Study of the interaction of thermoresponsive naogels with lipids
This proposal seeks to characterise the hydrophobic interaction of thermoresponsive nanogels designed for drug delivery through the skin with a lipid monolayer as a function of... -
Molecular architecture of monolayers formed by novel sterol-modified phosphol...
A family of sterol-modified glycerophospholipids (SML) have been synthesized in which the sn-1 or sn-2 position is covalently attached to cholesterol and the alternative... -
The calcuim mediation interaction of DNA with monolayers of DSPC and DOPE
The main objective of the present work is to complete some work aimed at gaining an understanding of the interaction of phospholipid membranes containing the neutral helper... -
Conformation of di-stearoyl-polyethylene glycol surfactants as enhancers of b...
This proposal relates to the structural studies of Di-stearoyl and di-palmitoyl Polyethylene glycol derivates as a function of the PEG head group at the air-water and the... -
Arctic Cloud Chemistry: Can the Halogen "explosion" oxidize material at air-w...
The Arctic climate is strongly influenced by clouds. The oxidative processing of pollutants in Arctic clouds affects droplet size and optical properties, important climatic... -
Molecular interactions between phospholipid monolayers and dimethylsulphoxide
Neutron reflectivity will be employed to investigate the interaction between dimethylsulphoxide and monomolecular films of phosphatidylcholine. The monolayer will be used as a... -
Conformational changes on interaction of cytochrome c with lipid monolayers.
The main objective of the present work is to gain an understanding of the interaction of the cationic protein, cyt c with anionic lipid membranes. This objective will be... -
Neutron reflectivity studies of the interaction of amphotericin with phosphol...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin (AmB) has created a demand for novel anti-fungal agents that can circumvent the pathogens¿... -
Heterogenous reactions between gas-phase hydroxyl radicals and organic films ...
Projected climate change is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects droplet size and reflectivity, important climatic effects.... -
The gas-phase oxidation of mixed organic films at the air-water interface ¿ t...
The Earth¿s climate is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects cloud droplet size and optical properties, important climatic... -
Surface structure of monolayers formed by novel di- and tri-chain cationic li...
The aim of the present study is to the determine, using specular neutron reflection (SNR), the structure of layers formed by novel tri-chain cationic lipids in combination with... -
Ozonation of organic films at the air-water interface of atmospheric aerosol
The Earth¿s climate is strongly influenced by atmospheric aerosols. Organic surfactant films on these aerosols influences their size, optical properties and ability to act as...
