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The effect of polymer therapeutics on the structure of mucin solutions toward...
Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key... -
Polymer chain conformations in solutions for electrospinning
This proposal is part of a research programme which is focused on nano-fibres prepared by electrospinning. The programme is centered on developing an understanding of the... -
Structure determination of gelled cellulose nanowhisker assemblies
We have developed a new and benign method for the production of cellulose based aerogels, highly porous materials with applications in insulation, drug delivery, gas storage,... -
Effect of terminal blocking groups on solution aggregation of short peptide f...
Short peptide sequences such as KLVFFAE form well defined beta sheet structures. Their further templating through hydrophobic interactions and hydrogen bonding is the principal... -
Understanding the properties of nucleobase functionalized nanostructures
We have recently prepared a number of new nucleobase functionalised polymers which undergo interesting and unexpected self-assembly. We hope to use SANS to explore further the... -
The Effect of Polydispersity on the Self Assembly of Diblock Copolymers
Block copolymers are of interest due to their ability to undergo microphase separation. Originally block copolymers were produced with a low polydispersity index (PDI) as they... -
Ionic liquid containing microemulsions
The aim of this experiment is to characterise several novel ionic liquid ¿ oil and ionic liquid ¿ water microemulsions via SANS prior to their use in the synthesis of metallic... -
Non-equilibrium kinetics in highly interacting polymer mixtures
We seek to investigate the non-equilibrium phenomena of a model polymer mixture by time-solved SANS and temperature jump experiments within (a) one-phase region and (b) one to... -
Compatibilisation of polymer blends using electrospinning
This proposal seachs time to establish the conditions under which electrospinning can be used to provide (non-equilibrium) mixtures of immiscible polymers. Such an outcome might... -
Reversible folding-unfolding and structural study in protein-ionic liquid sys...
It has been recently shown that reversible thermal folding-unfolding, stabilization and high solubility of proteins (e.g. lysozyme) can be achieved when dissolved in protic... -
Encapsulation of hydrophobic species in mixed micelles in polymer solutions
This proposal continues our investigations into film-forming polyelectrolyte-surfactant solutions. We have found that mixed micelle systems offer greater control over micelle... -
SANS studies of electrospun polystyrene-ammonia borane nanostructures
Increasing the density of hydrogen storage under ambient conditions is a critical requirement for the widespread introduction of low-carbon hydrogen vehicles. Ammonia borane... -
Effects of curvature and temperature on structure of lipid-polymer nanodiscs
Nanostructured lipid aggregates offer enormous potential as tools for membrane structural biology and biophysics. Styrene-Maleic Acid Lipid Particles have a number of attractive... -
Conformational behaviour of amphiphilic polymethacrylate-poly(acrylic acid) c...
We shall use SANS to investigate the conformational behaviour of a range of amphiphilic copolymers with varying architectures: graft, hyperbranched block, hyperbranched random,... -
Micellization in mixtures of surfactants used in fire-fighting foams
The aim is to probe the mixed micellar compositions of three common industrial fluorotelomer surfactants used in fire-fighting foam formulations (Figure 1) using contrast... -
Structural development in Whey protein polymer composite solutions for electr...
This is part of an on-going investigation into nano/micro scale sized polymer fibres at the University of Reading, prepared through the process of electrospinning. Currently we... -
Polymer electrolyte morphology investigated by SANS
Polymer electrolytes constitute a promising class of materials for rechargeable Li-batteries. The ionic conductivity behavior is dependent on the local morphology of the... -
SANS studies of mixed phsopholipid:sterol vesicles and their interaction with...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Nanoemulsions for dermatological drug delivery
Nanoemulsions have considerable potential for dermatological drug delivery. Small angle neutron scattering in combination with contrast variation will be used to characterize... -
Temperature-dependent structural behaviour of the collapse transition of high...
We shall use small angle neutron scattering to investigate the structural behaviour of the temperature sensitive highly branched poly(N-isopropyl acrylamide) [PNIPAM]. These...