18 datasets found

Challenges in cultivating microorganisms have limited the phylogenetic diversity of currently available microbial genomes. This is being addressed by advances in sequencing...

This is a large scale project with the sequencing co-funded by collaborators at the University of Cape Town and WT Core (I2818). This is a project aimed at deepening our...

The Two Weeks in the World research project has resulted in a dataset of 3100 clinically relevant bacterial genomes with pertaining metadata, collected from 59 diagnostic units...

Whole genome sequencing of bacterial isolates over a 1-year period from a hospital's intensive care units.

Collection of 3,087 bacterial metagenome-assembled genomes (MAGs) recovered from metagenomes available from the Sequence Read Archive. These MAGs comprise part of the data set...

Whole genome sequencing of pure cultured microbial isolates of multiple species as part of the Food and Drug Administration surveillance effort of pathogens in medical products.

<b>FDA-ARGOS project update</b> <p>FDA-ARGOS database updates may help researchers rapidly validate diagnostic tests and use qualified genetic sequences to...

High-quality (HQ) reference genomes are essential for understanding the phylogeny and function of uncultured microbes in complex microbial ecosystems. However, existing...

Here we present a comprehensive collection of 737 whole-genome sequenced bacterial isolates from humans to understand the blueprint of human gastrointestinal microbiota. This...

We used mNGS to detect pathogens in matched transbronchial lung biopsy (TBLB), bronchoalveolar lavage fluid (BALF), and bronchial needle brushing (BB) specimens from 39 patients...

We have developed a bladder-specific bacterial reference database consisting of 1134 genomes to aid in genomic, functional, and experimental analyses of the human bladder...

The goal of this work was to develop an approach for the rapid and sensitive detection of microbial contaminants at low abundance from low volume of samples during the...

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Advance the implementation of mNGS in pathogen diagnosis in clinics.

Bloodstream infection is a major cause of morbidity and mortality worldwide. Early pathogen detection and administration of appropriate antimicrobial therapy substantially...

Psoriasis can be provoked or exacerbated by environmental exposures such as certain microbiomes. The distinction between plaque psoriasis (PP) and guttate psoriasis (GP) in the...

This project aims to develop DNA and RNA sequencing as tools for pathogen discovery in a clinical setting.