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The Formation of Ion Channels in Phospholipid Bilayers by Puroindoline-a
Puroindolines are basic, cysteine rich proteins of ~13KDa, which have attracted significant interest due to their role in determining the endosperm texture of Wheat and seed... -
Analysis of the Self-Assembled S-layer Protein SpbA on Silanised Planar Silic...
This dataset has no description
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Membrane-stacking properties of myelin proteins
Myelin is the multilamellar structure that ensheaths axons and accelerates nervous impulses in the nervous system. The fine structure of myelin remains to be further... -
Characterisation of newly ordered sapphire blocks
This dataset has no description
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Amyloid β peptide and α-synuclein association at lipidmodel membranes
We plan to investigate the interaction between amyloid proteins and model biomembranes deposited on solid surfaces. The model membranes will be single zwitterionic and mixed... -
Effect of calcium ions and ionic strength on model bilayer structure
Calcium ions have been shown in a preliminary experiment to have a dramatic effect on the thickness and structure of free supported bilayer films. In this proposal we... -
Membrane-stacking properties of myelin proteins
Myelin is the multilamellar structure that ensheaths axons and accelerates nervous impulses in the nervous system. The fine structure of myelin remains to be further... -
Bilayer modification and charge screening by simple ions
Calcium ions have been shown in a preliminary experiment to have a dramatic effect on the thickness and structure of free supported DPPC bilayer films. At low concentrations... -
Magnetic contrast NR to resolve MscL opening under PXG challenge: influence o...
In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock, but, as with all ion channels, they have the potential to act as an Achilles heel,... -
Structural characterisation of vaccine-adjuvant interactions using neutron re...
This dataset has no description
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Chloride Intracellular Channel insertion into Tethered Bilayer Membranes
Part One of the proposal is concerned with the fundamental structure of the TBM and aims to determine: (i) the impact of spacer molecule length on the dimensions of the bilayer... -
Composition depth profiling of novel spray-coated plastic solar cell materials
We propose to study a range of new lower energy gap organic photovoltaic (OPV) materials deposited by spray coating using neutron reflectivity. The new materials to be studied... -
Determining the Induced Magnetism in Graphene by High-Angle Polarised Neutron...
The aim of this proposal is to measure the induced magnetic moment in graphene arising from the proximity effect in the vicinity of a ferromagnetic substrate using high-angle... -
Neutron Reflectivity study of lipopolysaccharide complexes with lateral domai...
We propose to investigate the role of lateral phase separation on LPS insertion into model membranes and the effects of target membrane structure and composition. A comparison... -
Selective recruitment of cholesterol to lipid rafts by multivalent protein bi...
Lipid raft microdomains offer a means to enhance the local concentration of membrane components as well as serve as a platform for raft associated endocytosis. Driven by... -
Head Group charging and anaesthetic Interaction with Model Bilayers
The mechanism of general anaesthetic action is poorly understood despite their widespread use. It is hoped that investigating the interaction of anaesthetics with lipid bilayers... -
Calcium mediated interaction between siRNA and phospholipid bilayers: the eff...
The main objective of the present study is to gain an understanding of the nature of the interaction of ¿phospholipid membranes¿ with small, interfering RNA (siRNA) in the... -
The Kinetics of Ethanol Adsorption into Cholesterol Rich Bilayers
In a recent experiment carried out on SURF we have shown that on addition of ethanol to a DPPC model membrane, the anaesthetic initially diffuses to the bilayer surface followed... -
Floating Bilayer Mimics of the Gram Negative Bacterial Outer Membrane
The gram-negative bacterial membrane is of extreme medical importance. The two main lipid components of the outer membrane are lipopolysaccharides (LPS's) and DOPE. We will... -
Phase Separation in Organic Photovoltaic Cells
Organic photovoltaic (OPV) cells have the potential to be the basis of a renewable energy source that is inexpensive and portable. Current state-of-the-art solution-processed...
