16 datasets found

Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element...

Lipopeptide surfactants are a group of interesting biosurfactants due to their natural origin and their high effectiveness at reducing interfacial tension. However, there is a...

In this proposal we request beamtime on the Inter reflectometer to study the unexpected adsorption behaviour of the surfactant bis(2-ethylhexyl) sulfosuccinate caesium salt...

Heavily bio-engineered monoclonal antibodies (mAbs) are an increasingly important trend in the biopharmaceutical industry. However, these mAbs are often destabilised by the...

In this part of proposed work, we wish to explore how antibiotics minocycline and tetracycline interact with model lipid bilayers in the form of SUVs, mimicking key features of...

With the biobased economy growing substantially and pressure to reduce reliance on palm and crude oil derived materials, it is vital that the Home and Personal Care industry...

We wish to understand how the concentration of surfactant mixtures in solution affects adsorption at lower temperatures; in particular, we wish to see how the composition of the...

Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation....

The lubrication of surfaces by oils is a key aspect of many academic and industrial problems with significant financial implications. In this experiment we would like to extend...

This proposal constitutes part of our ongoing study towards understanding how keratin, an important protein component of hair and skin, interacts with ionic surfactants using...

The interface of CaCO3 (calcite) and oil is of paramount importance in a number of key academic and industrial areas, not least oil recovery. Neutron reflection has proved to be...

Polymer-surfactant mixtures are widely used in commercial formulations in personal care, pharmaceutical and agrochemical, cleaning, automotive and food industries. The...

The lubrication of surfaces by oils is a key aspect of many academic and industrial problems with significant financial implications. In this experiment we would like to extend...

In this work we explore how our rationally designed peptide amphiphiles bind onto lipid monolayers using neutron reflection combined with deuterium labelling to the lipids,...

We have previously studied the adsorption of anti-beta-hCG at the hydrophilic silicon oxide/water interface and the subsequent binding by antigen hCG. We propose to extend this...

Acyl L-Carnitines are a group of novel surfactants with attractive physical and biological properties associated with their head group charge features. This work proposes to use...