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Quantifying antibiotic resistance using bacterial model membranes
The Gram negative bacterial outer membrane protects the bacterium from toxins such as antibiotics and is partially responsible for the rapid rise in antibiotic resistance in... -
Neutron Reflection Studies on Adsorption of Myristoyl-L-Carnitine at the Air/...
The acyl-L-carnitines are a group of novel surfactants. Following our recent home laboratory work to synthesize, purify and characterize them, the aim of this proposal is to... -
Neutron reflection from the surface of a liquid 3He-4He mixture
In our previous experiments we have investigated the surface properties of liquid 3He - 4He mixtures by neutron reflection. We have shown that in broad temperature range there... -
A study of protein adsorption via chelating lipids within a solid supported l...
The crystallisation of membrane proteins is of great interest, not least, to the pharmaceutical industry. We have recently begun a project aiming to investigate the role played... -
Latex - structure in binary mixtures - studies of crystallisation and stability
Recent experiments on SANS2D have indicated that small colloidal particles can act as macroions that screen the charged interactions of larger particles. This can cause changes... -
Kinetic Study of the Mechanistic Complexation Process Between DNA and Cationi...
We propose to use the new SANS2d to study the dynamic structural evolution in the couse of the formation of DNA-cationic polymer complexes. The dynamic process and the mixing... -
Probing the magnetic interface in Bi2Se3/CoFeB bilayers by polarized neutron ...
Topological insulators (TIs) are quantum materials having insulating properties in bulk, but display gapless conducting surface states. These conducting surface electronic... -
Impact of Protein Nanosheet Structure on Nanoscale Toughness
Cell adhesion and proliferation at the surface of liquids such as oil droplets is a surprising phenomenon as it is typically accepted in the field of bioengineering that cells... -
Structural studies of thermo-responsive nanogels at the oil-water interface
Nanogels because of their three-dimensional physical structure and tunable chemical properties as well as their stimuli-responsive nature have emerged as one of the most... -
Mixed H/F-Carbon surfactant monolayers for fire-fighting applications
The aim is to use Neutron Reflectivity (NR) to gain essential information on the adsorption properties of fluorocarbon/ hydrocarbon mixtures in commercial fire-fighting foam... -
Depth profiling fullerene-free organic solar cell blends using neutron reflec...
In Sheffield, 9% efficient organic solar cells have been made using a new non-fullerene acceptor called ITIC, when blended with semiconducting polymers. GIWAXS measurements have... -
Oxidative stress and lipid membrane disruption in bilayers containing polyuns...
Oxidation of lipid membranes is widely known to play a crucial role in many cellular processes and pathological conditions such as apoptosis, inflammation, infection, or sepsis,... -
Elemental Boron synthesized in supercritical metallic solvents at high pressu...
Our recent high (P,T) developments at PEARL beamline will allow us to study the kinetic and thermodynamic behavior of boron 11B under pressures up to 12 GPa and temperatures up... -
Non fullerene organic photovoltics
Organic solar cells (OPVs) are photovoltaic devices that can convert the energy from sunlight into electricity and have attracted much attention as a viable green energy source... -
A depth-resolved study of magnetoelectric coupling in multiferroic PMN-PT/FeR...
Multiferroic systems allow the modulation of magnetic properties through electric potentials. Advances in engineering atomic interfaces of heterogeneous thin-films have enabled... -
Neutron Reflectivity Study on Multi-domain DNA Molecular Motors
DNA is a versatile building material for nanotechnology. We have recently studied a surface-tethered single-domain DNA motor by neutron reflection (IR) for the first time. We... -
Forcing Sr2NiO2Cu2Se2 into the low spin regime under pressure
This is a proposal to drive the layered oxide chalcogenide Sr2NiO2Cu2Se2 from the high-spin state with long range magnetic order to the low-spin state, similar to that displayed... -
Biskyrmion Magnetic Nanodomains in the MnNiGa single-crystalline Study by Sma...
Magnetic skyrmions are topological vortex-like spin objects that were recently discovered in bulk chiral magnetic materials. Several months ago we discovered super stable... -
Ibuprofen containing surfactant monolayers: location and stiochiometry of ibu...
An increasing number of potential drug molecules are extremely water insoluble, limiting their commercialisation as medicines. Solubilisation of drug in surfactant micelles is a... -
Monitoring Gamma Prime Evolution in Superalloys using Small Angle Neutron Sca...
The aim of the experiment is to monitor the temporal evolution of gamma prime precipitates in three polycrystalline nickel base superalloys using Sans2D. This instrument is...
