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Interaction of the nucleic acid, DNA, with a model biomembranes of varying ri...
In this experiment we aim to investigate, using neutron reflectometry in combination with contrast variation, the intermolecular interaction between the nucleic acid, calf... -
Low temperature, high pressure phase transition of the Improper Ferroelectric...
We have found that the 134-perovskite, HgMn7O12 (HgAMnA3MnB4O12) exhibits improper ferroelectric coupling due to an unusual orbital ordering of the manganese cations on both... -
Co-adsorption of monoclonal antibodies and non-ionic surfactants at the air/l...
Nonionic surfactants usually do not show affinity to proteins and they work via competitive surface and interfacial processes in a binary mixture with protein. However, we show... -
Neutron reflectivity studies of the interaction of amphotericin with model ce...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin (AmB) has created a demand for novel anti-fungal agents that can circumvent the pathogens¿... -
Rietveld refinement of pulsed neutron transmission data
The analysis of Bragg edge in pulsed neutron transmission spectra is finding increasing use in combination with advances in energy selective imaging applications, and it is... -
Structural evidence of lipopolysaccharides functioning as receptors in antimi...
The global increase of bacterial resistance to antibiotics has led to increasing interest in research focusing on the development and characterization of new antimicrobial... -
Understanding light-induced changes to the miscibility of polymer/fullerene s...
Polymer/fullerene blends represent the most common form of organic solar cell. This proposal forms part of a wider effort in which our motivation is to complement solar cell... -
Incorporating outer membrane proteins in outer membrane models
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
Insertion of antimicrobial peptides into phospholipid monolayers at air/liqui...
We have designed a series of cationic peptides with different helix repeats that can kill bacteria but remain benign to mammalian host cells. The selectivity to cell types is... -
Determination of the detection limits and quantitative analysis reliability o...
Neutron diffraction offers one of the most interesting and meaningful methods for non destructive quantitative determination of the phase composition of materials. However, it... -
pH-control of swelling and charge neutralization of thin hydrogel films
Hydrogels are widely used in biomaterials science, much due to excellent protein resistance, and physicochemical properties similar to biological tissue. Charge neutrality is... -
Self-Organisation of Phospholipids on Au Electrodes
This experiment is part of a programme to study the effect of applied electric fields on the structure of biomimetic films formed at Au electrodes, with emphasis on... -
Using SERGIS, SESANS and NR to probe nanoscale cavities created within templa...
Nanoporous membranes fabricated by polymerization around soluble templates have found many applications in (bio)sensors, charge storage devices, filtration and catalysis.... -
Interaction between RNA and lipid monolayers
The objective of the suggested study is to reveal the structure formed when short ssRNA molecules (similar to miRNA) interact with lipid monolayers at the air-water interface.... -
The underwater Montefortino Helmet from Capo San Vito: neutron diffraction an...
The two Helmets subject of this proposal are kept in the Museo Archeologico Regionale Lilibeo - Baglio Anselmi of Marsala (Trapani, Italy). They were found in the seabed of Capo... -
Substrate-dependent structure of thin hydrogel films
Hydrogels are water-rich polymer networks made from natural or synthetic polymers, which are widely used in biomaterials, medicine and antifouling. We have developed PEG-based... -
Hydrophilic Melt Additive Segregation in Polyolefins
Small molecule additives are used in melt processing, sometimes to lubricate extrusion or to provide bespoke hydrophilic surfaces. Both applications require the additive to... -
Surfactants and additives at the metal-oil interface
The lubrication of surfaces by oils is a key aspect of many academic and industrial problems with significant financial implications. In this experiment we would like to extend... -
Tuning the Magnetic Properties of γ-Fe2O3 Fe3O4 Thin Films for Atom Tr...
In this work we will investigate how the magnetic properties of nanometer thick iron-oxide films can be manipulated by heating them in air. Our preliminary results indicate that... -
Exploring the exact morphology and self assembly characteristics of novel pol...
We would like to use SANS to explore the mechanism for preparation and properties of cylindrical micelles. We hope to obtain key information relating to the growth mechanism...
