-
Rapid microfluidic phase mapping of SDS:water:butanol
Sodium dodecyl sulfate (SDS) is an anionic surfactant, extensively employed in cosmetics and personal care, as well as in pharmaceuticals and food products. Surfactants are... -
Self-assembly of GFP-HMPA protein polymer conjugates: Effect of polymer hydro...
Conjugation of therapeutic proteins to polymers is well established but most methods result in multi-site and multiple conjugation, crosslinking resulting in lack of orientation... -
Molecular Collapse and Conformation of Low Molecular Mass Polyacrylic Acid an...
There is conflicting information about properties of polycrylic acid and its behaviour in aqueous solution. This proposal for an investigation by SANS that is directed at... -
The structure of the Bam complex, the Gram-negative outer membrane protein fo...
The proteins of the outer membrane of Gram-negative bacteria are critical for bacterial survival, from providing basic physiological functions, to impairing virulence and... -
Small Angle Neutron Scattering Study of the Adsorption of Amine ¿functionalis...
Amine-functionalised poly(alkylene oxides) are used extensively as swelling inhibitors in water-based drilling fluids. This study will broaden our understanding of the mechanism... -
A neutron study of capability of aggregation of the Abeta1-40, Abeta1-42 and ...
The aim of the proposed SANS experiment is to study the capability of aggregation, the shape and the size of aggregates of three amyloid peptides named (Abeta1-40, Abeta1-42 and... -
Characterisation of novel, sequence specific protein/protein and protein/DNA ...
Gene (nucleic acid) delivery to the cytosol or nucleus of a cell is, without the aid of a suitable delivery system, an inefficient process. Here the interaction of a defined... -
Structural analysis of amino acyl-tRNA-dependent Ligation Reactions in Bacter...
Assembly of the peptidoglycan later of bacterial cell walls is a validated target for anti-bacterial agents: the late transpeptidation and transglycosylation steps are inhibited... -
Competitive interactions in polymer-particle-surfactant blends
Many formulations comprise distinct chemical species that exhibit antagonistic or synergistic interactions that result in unpredictable behaviour. Previous work from our group... -
On the structure and composition of non-lamellar lipid-based liquid crystalli...
To better understand the properties of non-lamellar liquid crystalline nanoparticles (LCNP) as delivery vehicles, it is crucial to understand their internal structure and the... -
Mixed surfactants for positive synergism in dense CO2
This proposal aims to explore a cheaper and more environmental-benign surfactant system for yielding efficient water/CO2 microemulsions. The new surfactants permit high... -
Effect of pH on the complexation behaviour between Pluronic micelles, drugs a...
Pluronic micelles are attractive candidates as drug carriers. Despite the abundance of data on their association with various drugs, there is, in contrast, very little...
